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Key Documents

564613

Sigma-Aldrich

5-Amino-2-nitrobenzoic acid

97%

Synonym(s):

2-Nitro-5-aminobenzoic acid, 3-Carboxy-4-nitroaniline, NSC 74455

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About This Item

Linear Formula:
H2NC6H3(NO2)CO2H
CAS Number:
Molecular Weight:
182.13
Beilstein:
2107512
EC Number:
MDL number:
UNSPSC Code:
12352106
eCl@ss:
32160406
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

form

solid

reaction suitability

reaction type: solution phase peptide synthesis

mp

236-238 °C (lit.)

application(s)

peptide synthesis

SMILES string

Nc1ccc(c(c1)C(O)=O)[N+]([O-])=O

InChI

1S/C7H6N2O4/c8-4-1-2-6(9(12)13)5(3-4)7(10)11/h1-3H,8H2,(H,10,11)

InChI key

KZZWQCKYLNIOBT-UHFFFAOYSA-N

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Application

Reactant for:
  • Two-component dendritic chain reactions
  • Enzymic activation of hydrophobic self-immolative dendrimers
  • Preparation of insulin receptor tyrosine kinase activator
  • Preparation of polymer-bound diazonium salts using Merrifield resin-bound piperazine

Pictograms

Flame over circle

Signal Word

Danger

Hazard Statements

Hazard Classifications

Ox. Sol. 2

Storage Class Code

5.1B - Oxidizing hazardous materials

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Ewa Zabłotna et al.
Biochemical and biophysical research communications, 319(1), 185-188 (2004-05-26)
A tetrapeptide combinatorial library, considered as chromogenic substrates of bovine beta-trypsin, was synthesized by the solid phase method. The peptides contain an analog of p-nitroanilide, obtained by attaching 5-amino-2-nitrobenzoic acid (Anb(5,2)) to the C-termini. Deconvolution of the peptide library, performed
M Ramalingam et al.
Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy, 71(1), 23-30 (2008-01-08)
The FTIR and FT-Raman spectra of 5-amino-2-nitrobenzoic acid (ANB) have been recorded in the region 400-4000 cm(-1). The observed frequencies were assigned to different modes of vibrations on the basis of fundamental, combination and overtones. The geometry has been optimized
A Balamurugan et al.
Biosensors & bioelectronics, 24(4), 982-986 (2008-09-09)
Herein, we reported for the first time one step procedure for the preparation of cytochrome c (cyt c)-poly (5-amino-2-napthalenesulfonic acid) (PANS) modified glassy carbon electrode by cyclic voltammetrically (CV). Hereafter, we called the above modified electrode as cyt c-PANS electrode.
5-amino-2-nitrobenzoic acid as a reference material for the determination of gamma-GT activity.
S Yamadate et al.
Clinica chimica acta; international journal of clinical chemistry, 160(1), 63-67 (1986-10-15)
Yu Jin Park et al.
Clinical biochemistry, 50(12), 719-725 (2017-03-05)
The use of iodinated contrast media has grown in popularity in the past two decades, but relatively little attention has been paid to the possible interferential effects of contrast media on laboratory test results. Herein, we investigate medical contrast media

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