Skip to Content
Merck
All Photos(3)

Key Documents

515574

Sigma-Aldrich

Isoindoline

97%

Synonym(s):

1,3-Dihydro-2H-isoindole, 1,3-Dihydroisoindole, 2,3-Dihydro-1H-isoindole, 2-Azaindan

Sign Into View Organizational & Contract Pricing


About This Item

Empirical Formula (Hill Notation):
C8H9N
CAS Number:
Molecular Weight:
119.16
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

97%

refractive index

n20/D 1.57 (lit.)

bp

221 °C (lit.)

mp

17 °C (lit.)

density

1.05 g/mL at 25 °C (lit.)

storage temp.

2-8°C

SMILES string

C1NCc2ccccc12

InChI

1S/C8H9N/c1-2-4-8-6-9-5-7(8)3-1/h1-4,9H,5-6H2

InChI key

GWVMLCQWXVFZCN-UHFFFAOYSA-N

Application

Used to make a chiral diamine catalyst from L-proline for the asymmetric acylation of alcohols.

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

No data available

Flash Point(C)

No data available

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Teresa Mancilla-Percino et al.
Archiv der Pharmazie, 349(3), 175-185 (2016-01-15)
IC50 values were obtained for two series of isoindolines derived from α-amino acids over cyclooxygenase 1 and 2 (COX-1 and COX-2). In order to explain the biological activity observed, a structure-activity relationship (SAR) model was achieved for the tested compounds
Organic Syntheses, 83, 70-70 (2006)
Yulia Kaluzhny et al.
Alternatives to laboratory animals : ATLA, 43(2), 101-127 (2015-05-23)
The 7th Amendment to the EU Cosmetics Directive and the EU REACH Regulation have reinforced the need for in vitro ocular test methods. Validated in vitro ocular toxicity tests that can predict the human response to chemicals, cosmetics and other

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service