379409

3-Hydroxy-1,2-dimethyl-4(1H)-pyridone

98%

• Synonym(s): Deferiprone
• Empirical Formula (Hill Notation): C₇H₉NO₂
• CAS Number: 30652-11-0
• Molecular Weight: 139.15
• MDL number: MFCD00134497
• UNSPSC Code: 12352100
• PubChem Substance ID: 24863630
• NACRES: NA.22

Properties

• Assay: 98%
• form: powder
• mp: 272-275 °C (lit.)
• SMILES string: CN1C=CC(=O)C(O)=C1C
• InChI: 1S/C7H9NO2/c1-5-7(10)6(9)3-4-8(5)2/h3-4,10H,1-2H3
• InChI key: TZXKOCQBRNJULO-UHFFFAOYSA-N

Description

General description

3-Hydroxy-1,2-dimethyl-4(1H)-pyridone (Hdpp, Deferiprone) is a hydroxy ketone derivative. It reacts with uranyl salts [UO₂(NO₃)₂] in aqueous acidic solution to afford mono nuclear complexes ([UO₂(dpp)(Hdpp)₂(H₂O)]ClO₄). X-ray studies have been conducted to examine the structure and geometry of these complexes.

Application

3-Hydroxy-1,2-dimethyl-4(1H)-pyridone (OH-pyridone) may be used in the bacterial killing assays. It has been employed as hydroxyketone chelating agent and its cytotoxic action against oral human normal and tumor cell lines has been evaluated.

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves