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226904

Sigma-Aldrich

Methoxyamine hydrochloride

98%

Synonym(s):

O-Methylhydroxylamine hydrochloride, Methoxylamine hydrochloride

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About This Item

Linear Formula:
CH3ONH2 · HCl
CAS Number:
593-56-6
Molecular Weight:
83.52
Beilstein:
3589723
EC Number:
209-798-7
MDL number:
MFCD00012951
UNSPSC Code:
12352100
PubChem Substance ID:
24853598
NACRES:
NA.22

Quality Level

200

Assay

98%

form

solid

mp

151-154 °C (lit.)

solubility

alcohol: soluble(lit.)
water: soluble(lit.)

SMILES string

Cl.CON

InChI

1S/CH5NO.ClH/c1-3-2;/h2H2,1H3;1H

InChI key

XNXVOSBNFZWHBV-UHFFFAOYSA-N

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General description

Methoxyamine hydrochloride combines with human antithrombin III-thrombin complex to form an inactive thrombin.

Application

Methoxyamine hydrochloride was used as a reagent in the preparation of O-methyl oximes. It was also used in the synthesis of O-methyl oximes from aldehydes or ketones.

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT RE 1

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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M O Longas et al.
The Biochemical journal, 189(3), 481-489 (1980-09-01)
1. Cleavage of the human antithrombin III--thrombin complex with [14C]methoxyamine hydrochloride results in inactive thrombin and 14C-labelled antithrombin III. 2. Discontinuous polyacrylamide-gel electrophoresis of the reduced dissociation fragments of the complex in the presence of sodium dodecyl sulphate reveals two
Jean-Philippe Mevy et al.
Plants (Basel, Switzerland), 9(9) (2020-09-10)
Global change scenarios in the Mediterranean basin predict a precipitation reduction within the coming hundred years. Therefore, increased drought will affect forests both in terms of adaptive ecology and ecosystemic services. However, how vegetation might adapt to drought is poorly
Tetrahedron Letters, 47, 6045-6045 (2006)
Edouard Godineau et al.
Organic letters, 8(21), 4871-4874 (2006-10-06)
[reaction: see text] A formal [2+2+2] process has been devised that allows the stereocontrolled formation of ring-fused piperidines from allylsilanes possessing an oxime moiety. The cascade involves an intermolecular radical addition of an alpha-iodoacetate onto an allylsilane double bond, which
Chunmei Geng et al.
Scientific reports, 10(1), 700-700 (2020-01-22)
Depression is the most common disabling psychiatric disease, with a high prevalence and mortality. Chronic unpredictable mild stress (CUMS) is a well-accepted method used to mimic clinical depression. Recent evidence has consistently suggested that the cumulative effects of CUMS could
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