Skip to Content
Merck
All Photos(1)

Key Documents

209880

Sigma-Aldrich

5-Phenyl-o-anisidine

≥98%

Synonym(s):

2-Methoxy-5-phenylaniline

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
C6H5C6H3(OCH3)NH2
CAS Number:
Molecular Weight:
199.25
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22

Quality Level

Assay

≥98%

form

powder

mp

82-83 °C (lit.)

SMILES string

COc1ccc(cc1N)-c2ccccc2

InChI

1S/C13H13NO/c1-15-13-8-7-11(9-12(13)14)10-5-3-2-4-6-10/h2-9H,14H2,1H3

InChI key

DTYBRSLINXBXMP-UHFFFAOYSA-N

General description

5-Phenyl-o-anisidine is a promising monomer for polyanilines studies. X-ray Diffraction and DFT studies of 5-phenyl-o-anisidine (2-methoxy-5-phenylaniline) have been reported.

Application

5-Phenyl-o-anisidine (2-Methoxy-5-phenylaniline) was used in the synthesis of 2,4-diamino-5-methyl-6-substituted-pyrido[2,3-d]pyrimidines.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

X-ray Diffraction and DFT Studies of 2-Methoxy-5-phenylaniline.
Marques AT, et al.
Journal of Chemical Crystallography, 38(4), 295-299 (2008)
A Gangjee et al.
Journal of medicinal chemistry, 40(4), 479-485 (1997-02-14)
Nine novel 2,4-diamino-5-methyl-6-substituted-pyrido[2,3-d]pyrimidines, 2-10, were synthesized as potential inhibitors of Pneumocystis carinii dihydrofolate reductase (pcDHFR) and Toxoplasma gondii dihydrofolate reductase (tgDHFR). Compounds 2-5 were designed as conformationally restricted analogues of trimetrexate (TMQ), in which rotation around tau 3 was constrained

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service