1444300

Misoprostol

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): (±)-15-Deoxy-(16RS)-16-hydroxy-16-methylprostaglandin E₁ methyl ester
• Empirical Formula (Hill Notation): C₂₂H₃₈O₅
• CAS Number: 59122-46-2
• Molecular Weight: 382.53
• MDL number: MFCD00274550
• UNSPSC Code: 41116107
• PubChem Substance ID: 329750475
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: misoprostol
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: −20°C
• SMILES string: CCCCC(C)(O)C\C=C\[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCCCC(=O)OC
• InChI: 1S/C22H38O5/c1-4-5-14-22(2,26)15-10-12-18-17(19(23)16-20(18)24)11-8-6-7-9-13-21(25)27-3/h10,12,17-18,20,24,26H,4-9,11,13-16H2,1-3H3/b12-10+/t17-,18-,20-,22?/m1/s1
• InChI key: OJLOPKGSLYJEMD-URPKTTJQSA-N
• Gene Information: human ... PTGER3(5733)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Ph

Application

Misoprostol USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Diclofenac Sodium and Misoprostol Delayed-Release Tablets
• Misoprostol
• Misoprostol Dispersion

Biochem/physiol Actions

PGE₁ analog prodrug which is rapidly de-esterified to active "misoprostolic acid". Cited for extremely wide-ranging therapeutic effects, including prevention of NSAID-induced gastric ulceration, regulation of immunologic cascades, inhibition of platelet-activating factor (PAF), treatment of ethanol- and acetaminophen-induced hepatotoxicity and hepatitis, and stimulation of cartilage repair after injury.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS06,GHS08
• Signal Word: Danger
• Hazard Statements: H301,H360
• Precautionary Statements: P201 - P280 - P301 + P330 + P331 + P310 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Oral - Repr. 1B
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable