Skip to Content
Merck
All Photos(1)

Documents

1426002

USP

Methyldopa

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

Methyl-DOPA sesquihydrate, 3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine, MK-351, Methyl-L-DOPA

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C10H13NO4 · 1.5H2O
CAS Number:
41372-08-1
Molecular Weight:
238.24
Beilstein:
2417244
MDL number:
MFCD00004186
UNSPSC Code:
41116107
PubChem Substance ID:
329750434
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

methyldopa

manufacturer/tradename

USP

mp

≥300 °C

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

C[C@](N)(Cc1ccc(O)c(O)c1)C(O)=O

InChI

1S/C10H13NO4/c1-10(11,9(14)15)5-6-2-3-7(12)8(13)4-6/h2-4,12-13H,5,11H2,1H3,(H,14,15)/t10-/m0/s1

InChI key

CJCSPKMFHVPWAR-JTQLQIEISA-N

Gene Information

human ... ADRA2A(150) , ADRA2B(151) , ADRA2C(152)

Looking for similar products? Visit Product Comparison Guide

Related Categories

Application

Methyldopa USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Qi Chang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 805(2), 275-280 (2004-05-12)
A new method for the determination of tranexamic acid (TA) in human plasma using high performance liquid chromatography with tandem mass spectrometric detection was described. TA and the internal standard, methyldopa, was extracted from a 200 l plasma sample by
P A van Zwieten et al.
Hypertension (Dallas, Tex. : 1979), 6(5 Pt 2), II28-II33 (1984-09-01)
Clonidine (Catapres, Catapresan), guanfacine (Estulic), and methyldopa (Aldomet) are the prototypes of centrally acting antihypertensive drugs. Clonidine and guanfacine are lipophilic drugs that readily penetrate into the brain, where they stimulate alpha-adrenergic receptors in the pontomedullary region. The stimulation of
Li-Ting Liao et al.
Clinica chimica acta; international journal of clinical chemistry, 436, 72-77 (2014-05-13)
Uric acid measurement has become increasingly important, and electrochemically modified detection method based portable devices hold a dominant position in the market for point of care and self-monitoring of uric acid blood levels. However, there has been a lack of

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service