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1356916

USP

Lansoprazole

United States Pharmacopeia (USP) Reference Standard

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About This Item

Empirical Formula (Hill Notation):
C16H14F3N3O2S
CAS Number:
103577-45-3
Molecular Weight:
369.36
MDL number:
MFCD00866873
UNSPSC Code:
41116107
PubChem Substance ID:
329750232
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

lansoprazole

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

Cc1c(CS(=O)c2nc3ccccc3[nH]2)nccc1OCC(F)(F)F

InChI

1S/C16H14F3N3O2S/c1-10-13(20-7-6-14(10)24-9-16(17,18)19)8-25(23)15-21-11-4-2-3-5-12(11)22-15/h2-7H,8-9H2,1H3,(H,21,22)

InChI key

MJIHNNLFOKEZEW-UHFFFAOYSA-N

Gene Information

human ... ATP4A(495) , ATP4B(496)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Lansoprazole USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Lansoprazole Compounded Oral Suspension
  • Lansoprazole Delayed-Release Capsules

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Product No.
Description
Pricing

Y0000773

Lansoprazole, European Pharmacopoeia (EP) Reference Standard

Y0000774

Lansoprazole for peak identification, European Pharmacopoeia (EP) Reference Standard

1356927

Lansoprazole Related Compound A, United States Pharmacopeia (USP) Reference Standard

1356931

Lansoprazole Related Compound B, United States Pharmacopeia (USP) Reference Standard

BP872

Lansoprazole, British Pharmacopoeia (BP) Reference Standard

BP873

Lansoprazole impurity standard, British Pharmacopoeia (BP) Reference Standard

PHR3019

Lansoprazole Related Compound A, pharmaceutical secondary standard, certified reference material

PHR2956

Lansoprazole Related Compound B, certified reference material, pharmaceutical secondary standard

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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A modified high-performance liquid chromatographic method for the analysis of pantoprazole sodium in pharmaceutical dosage forms using lansoprazole as internal standard.
Ashour, Safwan, and Soulafa Omar.
Arabian Journal of Chemistry, 1-6 (2011)
T Iwahi et al.
Antimicrobial agents and chemotherapy, 35(3), 490-496 (1991-03-01)
The activities of various types of antiulcer agents against Helicobacter pylori (formerly called Campylobacter pylori) strains were determined by an agar dilution method. Among the compounds tested, two benzimidazole proton pump inhibitors, lansoprazole (AG-1749) and omeprazole, were found to have
Jong Sun Kim et al.
Gut and liver, 8(5), 480-486 (2014-09-18)
Many authors recommend performing a second-look endoscopy (SLE) to reduce the frequency of delayed bleeding after endoscopic submucosal dissection (ESD) for gastric neoplasms, but these recommendations have been made despite a lack of reliable evidence supporting the effectiveness of SLE.
Hiroto Miwa et al.
Journal of gastroenterology and hepatology, 30(5), 834-841 (2015-01-07)
Non-erosive reflux disease (NERD) and functional dyspepsia (FD) share some common features, and the appropriateness of managing these diseases independently has been questioned. A post-hoc subgroup analysis of the LEGEND study was performed to compare demographics and treatment response between
Yasunobu Yamashita et al.
PloS one, 9(5), e97419-e97419 (2014-05-23)
Lansoprazole is a potent anti-gastric ulcer drug that inhibits gastric proton pump activity. We identified a novel function for lansoprazole, as an inducer of anti-oxidative stress responses in the liver. Gastric administration of lansoprazole (10-100 mg/kg) to male Wistar rats
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