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Key Documents

8.18759

Sigma-Aldrich

Tetra-n-butylammonium hydroxide

(20% solution in water) for synthesis

Synonym(s):

N,N,N-Tributyl-1-butanaminium hydroxide, TBAH, Tetrabutylammonium hydroxide

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About This Item

UNSPSC Code:
12352107
NACRES:
NA.22

Quality Level

200

form

liquid

pH

14 (20 °C in H2O)

bp

102 °C/1013 hPa

density

0.99 g/cm3 at 20 °C

storage temp.

2-30°C

Application


  • Hydration structures of lactic acid: Research explored the hydration structures of lactic acid and characterized the ionic clathrate hydrate formed with a biological organic acid anion, utilizing Tetra-n-butylammonium hydroxide in this process (Muromachi et al., 2014).

  • Protection of ribonucleosides in RNA synthesis: A study demonstrated the use of Tetra-n-butylammonium hydroxide in the solid-phase synthesis of RNA sequences, particularly for the protection of 2′-hydroxyl groups of ribonucleosides (Cieslak et al., 2013).

  • Analysis of cosmetic products: Tetra-n-butylammonium hydroxide is used as a ion-pairing agent in the simultaneous analysis of various organic acids in cosmetic products by enhancing the extraction efficiency during high-performance liquid chromatography (Mikami et al., 2002).

  • Determination of calcium dobesilate in human plasma: The compound was employed in the ion-pairing extraction and high-performance liquid chromatography for the determination of calcium dobesilate in human plasma, highlighting its utility in clinical analytical methods (Rona and Ary, 2001).

Analysis Note

Assay (acidimetric): 18.0 - 22.0 %
Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Statements

H314 - H317

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1 - Skin Sens. 1

Storage Class Code

8A - Combustible, corrosive hazardous materials

WGK

WGK 3

Certificates of Analysis (COA)

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