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Sigma-Aldrich

1,4-Butanediol diglycidyl ether

technical grade, 60%

Synonym(s):

1,4-Bis(2,3-epoxypropoxy)butane, 1,4-Bis(glycidyloxy)butane, 1,4-Bis(oxiran-2-ylmethoxy)butane, 1,4-Butylene glycol diglycidyl ether, Tetramethylene glycol diglycidyl ether

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About This Item

Empirical Formula (Hill Notation):
C10H18O4
CAS Number:
2425-79-8
Molecular Weight:
202.25
Beilstein:
115238
EC Number:
219-371-7
MDL number:
MFCD00005146
UNSPSC Code:
12162002
PubChem Substance ID:
24847603
NACRES:
NA.23

grade

technical grade

Quality Level

200

vapor pressure

~10 mmHg ( 20 °C)

form

liquid

concentration

60%

refractive index

n20/D 1.453 (lit.)

bp

266 °C (lit.)

density

1.1 g/mL at 25 °C (lit.)

SMILES string

C(CCOCC1CO1)COCC2CO2

InChI

1S/C10H18O4/c1(3-11-5-9-7-13-9)2-4-12-6-10-8-14-10/h9-10H,1-8H2

InChI key

SHKUUQIDMUMQQK-UHFFFAOYSA-N

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General description

1,4-Butanediol diglycidyl ether(BDDE) is a homobifunctional monomer with two epoxide groups, widely used to modify the viscosity of epoxy resins. It is also used as a cross-linking agent to synthesize polymer networks.

Application

1,4-Butanediol diglycidyl ether can be used:
  • As a cross-linking agent to prepare hyaluronic acid dermal fillers This crosslinking process enhances the gel-like consistency of the filler, making it more durable and longer-lasting.
  • As a monomer to prepare epoxy-based graphene nanocomposites that have potential applications in the field of flexible electronics, corrosion resistance coatings, and conductive adhesives. BDDE is chosen for its desirable properties such as low viscosity, good reactivity, and compatibility with graphene.

Pictograms

CorrosionExclamation mark
GHS05,GHS07

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 2

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Comparative physicochemical analysis among 1, 4-butanediol diglycidyl ether cross-linked hyaluronic acid dermal fillers
Nicola Zerbinati, et al.
Gels, 7, 139-139 (2021)
D S Pepper
Molecular biotechnology, 2(2), 157-178 (1994-10-01)
Three different coupling chemistries that have been tried and tested for use in affinity chromatography are described. These methods are particularly recommended for use by workers who do not have access to, or do not wish to use, complex organic
Petr Kubán et al.
Analytical chemistry, 79(14), 5462-5467 (2007-06-21)
The preparation and performance of a multilayered stationary phase for open tubular anion exchange chromatography in relatively large bore (75 microm diameter) columns are described. The inner surface of a fused-silica capillary tube is coated with up to 25 successive
Cheng Chen et al.
Biotechnology and applied biochemistry, 45(Pt 2), 87-92 (2006-05-25)
At present, the common tool for affinity purification of IgG is immobilized Protein A, which is separated from native cell-wall components of Staphylococcus aureus. It is complicated and costly to prepare natural Protein A. ZZ protein is a synthetic Fc
R Zeeman et al.
Journal of biomedical materials research, 46(3), 424-433 (1999-07-09)
Crosslinking of dermal sheep collagen (DSC) was accomplished using 1, 4-butanediol diglycidyl ether (BDDGE). At pH values > 8.0, epoxide groups of BDDGE will react with amine groups of collagen. The effects of BDDGE concentration, pH, time, and temperature were
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