P0119
Anti-Purinergic Receptor P2Y14 (extracellular) antibody produced in rabbit
affinity isolated antibody, lyophilized powder
Synonym(s):
Anti-GPR105, Anti-P2YR14
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.41
Recommended Products
biological source
rabbit
Quality Level
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
lyophilized powder
species reactivity
human, rat
technique(s)
western blot: 1:200 using rat brain and lung lysates, and rat heart membranes
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... P2RY14(9934)
rat ... P2ry14(171108)
Immunogen
peptide CIELKSELGRKWHKASN corresponding to residues 172-188 of human P2Y14 extracellular loop.
Target description
P2Y14 belongs to the P2Y receptor family that is part of the G-protein coupled receptor superfamily. P2Y14 is expressed in several tissues including brain, lung, and several cells of hematopoietic origin such as T lymphocytes and dendritic cells. This receptor is apparently involved in chemotaxis, maturation of immature dendritic cells, and neuroimmune regulation.
Physical form
Lyophilized from phosphate buffered saline, pH 7.4, containing 1% BSA and 0.05% sodium azide.
Reconstitution
Reconstitute the lyophilized vial with 50 μL or 200 μL deionized water, depending on package size. Further dilutions should be made using a carrier protein such as BSA (1-3%).
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Storage Class Code
11 - Combustible Solids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Jennifer Patritti Cram et al.
eLife, 11 (2022-03-22)
Neurofibromatosis type 1 (NF1) is characterized by nerve tumors called neurofibromas, in which Schwann cells (SCs) show deregulated RAS signaling. NF1 is also implicated in regulation of cAMP. We identified the G-protein-coupled receptor (GPCR) P2ry14 in human neurofibromas, neurofibroma-derived SC
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