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Sigma-Aldrich

Ammonium chloride

ACS reagent, ≥99.5%

Synonym(s):

Salmiac

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About This Item

Linear Formula:
NH4Cl
CAS Number:
Molecular Weight:
53.49
Beilstein:
4371014
EC Number:
MDL number:
UNSPSC Code:
12352300
eCl@ss:
38050207
PubChem Substance ID:
NACRES:
NA.21

grade

ACS reagent

Quality Level

Agency

suitable for SM 5210

vapor density

1.9 (vs air)

vapor pressure

1 mmHg ( 160.4 °C)

Assay

≥99.5%

form

powder, crystals or chunks

impurities

≤0.005% insolubles

ign. residue

≤0.01%

pH

4.5-5.5 (25 °C, 5%)

mp

340 °C (subl.) (lit.)

anion traces

phosphate (PO43-): ≤2 ppm
sulfate (SO42-): ≤0.002%

cation traces

Ca: ≤0.001%
Fe: ≤2 ppm
Mg: ≤5 ppm
heavy metals: ≤5 ppm (by ICP)

SMILES string

N.Cl

InChI

1S/ClH.H3N/h1H;1H3

InChI key

NLXLAEXVIDQMFP-UHFFFAOYSA-N

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General description

Crystals of ammonium chloride (NH4Cl) belong to the cubic crystal system. It can be synthesized by reacting HCl with aqueous ammonia solutions. NH4Cl is formed as a by-product during soda manufactured by Solvay process.

Application

Ammonium chloride (NH4Cl) has been used as one of the components of red blood cell (RBC) lysis buffer for use in various studies. It may be used as a catalyst in the preparation 3,4-dihydropyrimidin-2-(1H)-ones.
Inorganic ammonium ions (NH4+) effectively catalyze the aldol condensation of carbonyl compounds. It serves as a source of nitrogen during the preparation of trimethylamine hydrochloride (TMA·HCl).

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Mark E Kusek et al.
Journal of visualized experiments : JoVE, (83)(83), e50823-e50823 (2014-01-17)
Mucosal surfaces serve as protective barriers against pathogenic organisms. Innate immune responses are activated upon sensing pathogen leading to the infiltration of tissues with migrating inflammatory cells, primarily neutrophils. This process has the potential to be destructive to tissues if
Immune Cell Isolation from Mouse Femur Bone Marrow.
Liu X and Quan N.
Bio-protocol, 5(20) (2015)
Selective Synthesis of Trimethylamine by Catalytic N-Methylation of Ammonia and Ammonium Chloride by utilizing Carbon Dioxide and Molecular Hydrogen.
Beydoun K, et al.
ChemCatChem, 8(1), 135-138 (2016)
514502
CorpBase ID (for auto-filling citation data) null
Romina Frare et al.
FEMS microbiology letters, 367(23) (2020-11-27)
Nitrogen is a most important nutrient resource for Escherichia coli and other bacteria that harbor the glnKamtB operon, a high-affinity ammonium uptake system highly interconnected with cellular metabolism. Although this system confers an advantage to bacteria when growing under nitrogen-limiting

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Related Content

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

This page is intended to make it easier to find the consumables you need based on the analytical method you’re using. Methods included on this page come from the EPA, Standard Methods and ASTM.

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