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Furaltadone

VETRANAL®, analytical standard

Synonym(s):

5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidinone

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About This Item

Empirical Formula (Hill Notation):
C13H16N4O6
CAS Number:
Molecular Weight:
324.29
Beilstein:
8130725
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

VETRANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

clinical testing

format

neat

storage temp.

2-8°C

SMILES string

[O-][N+](=O)c1ccc(\C=N\N2CC(CN3CCOCC3)OC2=O)o1

InChI

1S/C13H16N4O6/c18-13-16(14-7-10-1-2-12(22-10)17(19)20)9-11(23-13)8-15-3-5-21-6-4-15/h1-2,7,11H,3-6,8-9H2/b14-7+

InChI key

YVQVOQKFMFRVGR-VGOFMYFVSA-N

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General description

Furaltadone is a nitrofuran drug, with broad-spectrum antimicrobial activity. It is widely used in veterinary medicine for intensive animal production, especially in pigs, poultry, fish and to provide resistance against infections caused by Escherichia coli and Salmonella.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. Furaltadone may be used as an analytical reference standard for the quantification of the analyte in milk samples and poultry eggs using different chromatography techniques.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Legal Information

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Acute Tox. 4 Oral

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Determination of nitrofurantoin, furazolidone and furaltadone in milk by high-performance liquid chromatography with electrochemical detection
Diaz G.T, et al.
Analytical Methods : Advancing Methods and Applications, 764(2), 243-248 (1997)
A Stammati et al.
Cell biology and toxicology, 13(2), 125-130 (1997-02-01)
Nitrofuran drugs have been studied on cellular systems in order to develop in vitro tests for safety assessment of food contaminants. In the present study we have tested furaltadone on three cell lines (HEp-2, Caco-2 and V79), using the same
B Murugasu-Oei et al.
The Journal of antimicrobial chemotherapy, 46(6), 917-919 (2000-12-05)
Depletion of oxygen triggers the shift-down of Mycobacterium bovis BCG to a state of dormancy. Bacilli in their dormant state are resistant to standard anti-mycobacterials. The nitroimidazole metronidazole was the first compound identified to show bactericidal activity against dormant tubercle
L P Jager et al.
European journal of pharmacology, 331(2-3), 325-331 (1997-07-23)
Changes in the biogenesis of corticosteroids caused by nitrofurans were studied. The three nitrofurans used: furazolidone, furaltadone and nitrofurantoin, altered the steroid production/release by porcine adrenocortical cells in vitro during 1 h incubations. With pregnenolone as a substrate the nitrofurans
Sara Leston et al.
Chemosphere, 82(7), 1010-1016 (2010-11-27)
The use of pharmaceuticals in the food production industry as prophylatic and therapeutic agents is necessary to promote animal health, but may entail significant consequences to natural ecosystems, especially in the cases of overdosing and use of banned pharmaceuticals. The

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