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Key Documents

05091

Sigma-Aldrich

3,5-Dimethylpyrazole

produced by Wacker Chemie AG, Burghausen, Germany, ≥99.0% (GC)

Synonym(s):

3,5-Dimethyl-1H-pyrazole

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About This Item

Empirical Formula (Hill Notation):
C5H8N2
CAS Number:
Molecular Weight:
96.13
Beilstein:
106325
EC Number:
MDL number:
UNSPSC Code:
12352100
eCl@ss:
39160503
PubChem Substance ID:
NACRES:
NA.22

grade

produced by Wacker Chemie AG, Burghausen, Germany

Quality Level

Assay

≥99.0% (GC)

bp

218 °C (lit.)

mp

105-108 °C (lit.)

SMILES string

Cc1cc(C)[nH]n1

InChI

1S/C5H8N2/c1-4-3-5(2)7-6-4/h3H,1-2H3,(H,6,7)

InChI key

SDXAWLJRERMRKF-UHFFFAOYSA-N

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Pictograms

Health hazardExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - STOT RE 2

Target Organs

Liver

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Alessandra Del Roso et al.
Experimental gerontology, 38(5), 519-527 (2003-05-14)
Autophagy is a universal, highly regulated mechanism responsible for the degradation of long-lived proteins, cytomembranes and organelles during fasting and may be the cell repair mechanism that mediates the anti-ageing effects of calorie restriction (Bergamini and Gori, 1995). The function
E Bergamini et al.
The American journal of physiology, 266(1 Pt 1), G118-G122 (1994-01-01)
Regulation of liver macroautophagy and protein degradation by hormones and direct regulatory amino acids were studied in male 2-mo-old Sprague-Dawley albino rats with the use of the antilipolytic agent 3,5'-dimethylpyrazole (DMP; 12 mg/kg body wt ip) as a stimulatory agent.
Gabriella Cavallini et al.
Autophagy, 3(1), 26-27 (2006-09-12)
Autophagy is a major intracellular degradation/recycling system ubiquitous in eukaryotic cells. It contributes to the turnover of cellular components by delivering portions of the cytoplasm and organelles to lysosomes, where they are digested. Starvation-induced autophagy is required for maintaining an
Effects of antilipolytic agents on peroxisomal beta-oxidation of fatty acids in rat liver.
T Locci-Cubeddu et al.
Biochemical pharmacology, 32(11), 1807-1809 (1983-06-01)
C Redekopp et al.
Journal of endocrinological investigation, 7(4), 277-281 (1984-08-01)
The inhibitory and stimulatory effects of somatostatin analogues on growth hormone secretion have been studied in the sheep. Plasma immunoreactive growth hormone (GH) was stimulated by the iv administration of the antilipolytic compound 3,5-dimethylpyrazole and was followed by infusion of

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