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Sigma-Aldrich

L-α-Lecithin

≥97% (choline basis), solid, lipotropic agent, Calbiochem

Synonym(s):

L-α-Lecithin, Soybean

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12352211
NACRES:
NA.77

product name

L-α-Lecithin, Soybean, L-α-Lecithin, Soybean, CAS 8002-43-5, is a concentrate of soybean lecithin consisting of more than 94% phosphatidylcholine and less than 2% triglycerides.

Quality Level

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze

color

light yellow

solubility

RPMI culture medium: 10 mg/mL, turbid
chloroform: 200 mg/mL

shipped in

wet ice

storage temp.

−20°C

General description

Concentrate of soybean lecithin consisting of more than 94% phosphatidylcholine and less than 2% triglycerides. Composed mainly of linoleic acid (62 - 65%) and palmitic acid (15 - 17%) esters.
Lecithins are typically phospholipids, consisting of phosphoric acid with choline, glycerol, and one (lyso-forms) or two fatty acids. It is a yellow to brown fatty substance, that can be obtained from both plant and animal sources, with soy lecithin and sunflower lecithin being common varieties. They are present in animal products due to dietary sources and de novo synthesis. Commercial lecithin, often derived from soybeans, is widely employed in the food industry as an emulsifier in processed goods such as ice creams and salad dressings. Lecithin supplements are commonly used to manage high cholesterol levels, support lactation, and serve as antiulcer agents. Lecithin, also known as phosphatidylcholine, serves as a precursor for choline and is involved in the synthesis of the neurotransmitter acetylcholine, with its levels correlating with those of choline and acetylcholine. Moreover, it plays a role in complex intracellular processes, including the regulation of cellular membrane permeability.

Application

L-α-Lecithin, Soybean has been used in film preparation and as a surfactant for the preparation and characterization of the nanoemulsion. It has also been used as a component in solubilization buffer to incubate heavy SR (HSR) for affinity purification of RyR1 (ryanodine receptor).

Biochem/physiol Actions

Cell permeable: no
Product does not compete with ATP.
Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 2 weeks at -20°C.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Lecithin
Shahira M E, et al.
The Journal of Biological Chemistry, 375-386 (2022)
Lecithin
Shahira M E, et al.
Test, 375-386 (2022)
Mania and Agitation
Kapalka GM
The Journal of biological chemistry (2010)
Lecithin
Shahira M E, et al.
The Journal of biological chemistry, 375-386 (2022)
Application of nanoemulsions (W/O) of extract of Opuntia oligacantha CF forst and orange oil in gelatine films
Espino-Manzano SO, et al.
Molecules (Basel), 25, 3487-3487 (2020)

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