N-046
(+)-Norpseudoephedrine hydrochloride solution
100 μg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®
Synonym(s):
Cathine hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C9H14ClNO
CAS Number:
Molecular Weight:
187.67
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
grade
certified reference material
Quality Level
form
liquid
feature
Snap-N-Spike®/Snap-N-Shoot®
packaging
ampule of 1 mL
manufacturer/tradename
Cerilliant®
drug control
Narcotic Licence Schedule B (Switzerland); psicótropo (Spain); Decreto Lei 15/93: Tabela IIB (Portugal)
concentration
100 μg/mL in methanol (as free base)
technique(s)
gas chromatography (GC): suitable
liquid chromatography (LC): suitable
application(s)
forensics and toxicology
format
single component solution
storage temp.
−20°C
SMILES string
Cl.C[C@H](N)[C@@H](O)c1ccccc1
InChI
1S/C9H13NO.ClH/c1-7(10)9(11)8-5-3-2-4-6-8;/h2-7,9,11H,10H2,1H3;1H/t7-,9+;/m0./s1
InChI key
DYWNLSQWJMTVGJ-DKXTVVGFSA-N
General description
A certified reference solution suitable for use as starting material in calibrators or controls for a variety of LC/MS or GC/MS applications, from clinical toxicology and forensic analysis to urine drug testing and sports testing. (+)-Norpseudoephedrine, also known as cathine, is a psychoactive stimulant of the phenethylamine and amphetamine classes.
Application
- Phytochemical Profiling and Therapeutic Activities: (+)-Norpseudoephedrine hydrochloride solution is utilized in phytochemical profiling studies, specifically analyzing the toxicity, wound healing, analgesic, and anti-inflammatory properties of Musa paradisiaca L. stem extracts. This research enhances the understanding of natural products in pharmaceutical applications, particularly for their therapeutic potential (Ekweogu et al., 2024).
- Chiral Analysis of Stimulant Drugs: The solution is critical in the development and application of a chiral high-performance liquid chromatography-tandem mass spectrometry method for forensic analysis. This method is used to determine the presence of related amphetamine-type stimulants, providing essential data for law enforcement and drug regulation agencies (Schwelm et al., 2020).
- Microbial Production of Phenylalkylamines: (+)-Norpseudoephedrine hydrochloride serves as a biochemical tool in studies focused on the microbial production of ephedrine and pseudoephedrine, revealing significant implications for the manufacturing of pharmaceuticals and enhancing our understanding of metabolic pathways (Morris et al., 2018).
- Improved Detection Methods for Cathinones: This compound is integral to the improved gas chromatography method for detecting active principles in Catha edulis, demonstrating its utility in identifying and quantifying natural sources of cathinones, which are important for both medical research and drug enforcement (Dell′acqua et al., 2013).
- Chiral Capillary Electrophoresis: Used in chiral capillary electrophoresis for methamphetamine profiling, (+)-Norpseudoephedrine hydrochloride solution assists in distinguishing isomers in forensic samples, which is critical for the precise identification of controlled substances in forensic settings (Iwata et al., 2013).
Legal Information
CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
Snap-N-Shoot is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany
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Description
Pricing
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
Storage Class Code
3 - Flammable liquids
WGK
WGK 2
Flash Point(F)
49.5 °F - closed cup
Flash Point(C)
9.7 °C - closed cup
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Raz Krizevski et al.
Journal of ethnopharmacology, 114(3), 432-438 (2007-10-12)
Khat (Catha edulis Forsk., Celastraceae) is a perennial shrub that was introduced to Israel by Yemenite immigrants. Khat young leaves are chewed as a stimulant. The main stimulating active principles in this plant are the phenylpropylamino alkaloids (-)-cathinone [(S)-alpha-aminopropiophenone], (+)-cathine
Hesham Abdul Aziz et al.
The journal of sexual medicine, 6(3), 682-695 (2009-01-16)
Khat (Catha edulis) is an evergreen tree/shrub that is thought to affect sexual motivation or libido. Its positive effect on sexual desire is more frequently observed in females than in males and occurs when khat is chewed. Thus, khat's effects
Osquel Barroso et al.
Drug testing and analysis, 4(5), 320-329 (2011-05-07)
Due to its stimulatory effects on the central nervous system, and its structural similarity to banned stimulants such as ephedrine and methamphetamine, pseudoephedrine (PSE) at high doses is considered as an ergogenic aid for boosting athletic performance. However, the status
Veniero Gambaro et al.
Forensic science international, 217(1-3), 87-92 (2011-10-26)
In the last years, all the vegetable material supposed to belong to the Catha Edulis species, seized at the Malpensa and Orio al Serio airports, were analyzed in our laboratory on behalf of the Tribunals of Busto Arsizio and Bergamo
K Deventer et al.
Drug testing and analysis, 1(5), 209-213 (2010-04-01)
Until the end of 2003 a urinary concentration of pseudoephedrine exceeding 25 microg/mL was regarded as a doping violation by the World Anti-Doping Agency. Since its removal from the prohibited list in 2004 the number of urine samples in which
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