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Key Documents

800821C

Avanti

18:0-16:0 DG

1-octadecanoyl-2-hexadecanoyl-sn-glycerol, chloroform

Synonym(s):

1-stearoyl-2-palmitoyl-sn-glycerol; DG(18:0/16:0/0:0); 110883

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About This Item

Empirical Formula (Hill Notation):
C37H72O5
CAS Number:
14015-55-5
Molecular Weight:
596.96
UNSPSC Code:
12352211
NACRES:
NA.25

Assay

>99% (TLC)

form

liquid

packaging

pkg of 1 × 5 mL (800821C-5mg)

manufacturer/tradename

Avanti Research™ - A Croda Brand 800821C

concentration

1 mg/mL (800821C-5mg)

lipid type

neutral glycerides
neutral lipids

shipped in

dry ice

storage temp.

−20°C

InChI

1S/C37H72O5/c1-3-5-7-9-11-13-15-17-18-20-21-23-25-27-29-31-36(39)41-34-35(33-38)42-37(40)32-30-28-26-24-22-19-16-14-12-10-8-6-4-2/h35,38H,3-34H2,1-2H3

InChI key

VYQDALBEQRZDPL-UHFFFAOYSA-N

General description

18:0-16:0 DG, also called 1-stearoyl-2 palmitoyl-sn-glycerol diacylglycerol (DAG), comprises a glycerol backbone with two carboxylic acids covalently linked to the sn-1 and sn-2 position.

Application

18:0-16:0 DG may be used in the standard curve generation for liquid chromatography-mass spectrometry (LC-MS) analysis.

Biochem/physiol Actions

18:0-16:0 DG, also called 34:0-DG, is phosphorylated by diacylglycerol kinase δ at high glucose levels. DG participates in protein kinase C activation and is a second messenger for many signaling events.

Packaging

30 mL Amber Narrow Mouth Glass Bottle with Screw Cap (800821C-5mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3

Target Organs

Central nervous system, Liver,Kidney

WGK

WGK 3

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Dimer ion formation and intermolecular fragmentation of 1, 2-diacylglycerols revealed by electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry for more comprehensive lipid analysis
Muller C, et al.
Rapid Communications in Mass Spectrometry, 28(15), 1735-1744 (2014)
Constanze Müller et al.
Rapid communications in mass spectrometry : RCM, 28(15), 1735-1744 (2014-07-01)
The ionization of neutral diacylglycerols (DAGs) by electrospray ionization mass spectrometry (ESI-MS) is challenging compared with other lipid classes which possess ionic head group conjugations. Although ESI-MS is the method of choice in lipidomic analysis, it is questionable whether all
Chiaki Murakami et al.
Analytical biochemistry, 526, 43-49 (2017-03-21)
Phosphatidylcholine (PC)-specific phospholipase C (PC-PLC) hydrolyzes PC to generate the second messenger 1,2-diacylglycerol (DG) and phosphocholine. PC-PLC plays pivotal roles in inflammation, carcinogenesis, tumor progression, atherogenesis, and subarachnoid hemorrhage. Although the activity of PC-PLC in mammalian tissues was discovered approximately

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