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900601

Sigma-Aldrich

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride

≥95%

Synonym(s):

Formyl sulfonyl fluoride alkyne, Probe building block

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About This Item

Empirical Formula (Hill Notation):
C12H13FO3SSi
CAS Number:
Molecular Weight:
284.38
UNSPSC Code:
12352200
NACRES:
NA.22

Assay

≥95%

form

solid

reaction suitability

reaction type: click chemistry

storage temp.

−20°C

SMILES string

O=C([H])C1=CC(S(=O)(F)=O)=CC(C#C[Si](C)(C)C)=C1

Application

3-Formyl-5-((trimethylsilyl)ethynyl)benzenesulfonyl fluoride is used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and aldehyde synthetic handle. When appended to a ligand or pharmacophore through its formyl group, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

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Product No.
Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

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Articles

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

In partnership with Pfizer chemists, we have compiled a collection of trifunctional building blocks to enable development of probes.

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