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Quality Level
Assay
97%
mp
90-94 °C (lit.)
SMILES string
Nc1ccnc(Cl)c1
InChI
1S/C5H5ClN2/c6-5-3-4(7)1-2-8-5/h1-3H,(H2,7,8)
InChI key
BLBDTBCGPHPIJK-UHFFFAOYSA-N
General description
4-Amino-2-chloropyridine is a chloroaminoheterocyclic compound. It readily undergoes Suzuki-Miyaura coupling with phenylboronic acid.
Application
4-Amino-2-chloropyridine may be used in the preparation of:
- 3-deazacytosine
- 7-substituted 1-alky-1,4-dihydro-4-oxo-1,6-naphthyridine-3-carboxylic acids
- 1,6-naphthyridines
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Find documentation for the products that you have recently purchased in the Document Library.
Pyridone-carboxylic Acids as Antibacterial Agents. I. Synthesis and Antibacterial Activity of 1-Alkyl-1, 4-dihydro-4-oxo-1, 8-and 1, 6-naphthyridine-3-carboxylic Acids.
Chemical & Pharmaceutical Bulletin, 30(7), 2399-2409 (1982)
Preparation and biological activity of various 3-deazapyrimidines and related nucleosides.
Journal of medicinal chemistry, 16(3), 294-297 (1973-03-01)
A highly active catalyst for Suzuki-Miyaura cross-coupling reactions of heteroaryl compounds.
Angewandte Chemie (International ed. in English), 45(21), 3484-3488 (2006-04-28)
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