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376914

Sigma-Aldrich

Poly(methyl methacrylate-co-methacrylic acid)

average Mw ~34,000 by GPC, average Mn ~15,000 by GPC

Synonym(s):

Poly(methacrylic acid-co-methyl methacrylate)

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About This Item

CAS Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23

feed ratio

1:0.016 (methyl methacrylate:methacrylic acid)

mol wt

average Mn ~15,000 by GPC
average Mw ~34,000 by GPC

inherent viscosity

0.19 dL/g(lit.)

transition temp

Tg 105 °C

InChI

1S/C5H8O2.C4H6O2/c1-4(2)5(6)7-3;1-3(2)4(5)6/h1H2,2-3H3;1H2,2H3,(H,5,6)

InChI key

IWVKTOUOPHGZRX-UHFFFAOYSA-N

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Application

  • Ultrafine Nanoparticles of Poly(Methyl Methacrylate-co-Methacrylic Acid) Loaded with Aspirin: This study focuses on the preparation and potential therapeutic applications of biocompatible nanoparticles loaded with aspirin, highlighting their suitability for medical use (López-Muñoz et al., 2019).
  • Biocompatible and biodegradable ultrafine nanoparticles of poly (methyl methacrylate-co-methacrylic acid) prepared via semicontinuous heterophase: Discusses the synthesis of biodegradable nanoparticles for potential biomedical applications, emphasizing their eco-friendly nature and suitability for drug delivery systems (Saade et al., 2016).
  • Synthesis and characteristics of poly(methyl methacrylate‐co‐methacrylic acid)/poly(methacrylic acid‐co‐N‐isopropylacrylamide) thermosensitive semi‐hollow latex: Explores the unique properties of thermosensitive latex particles for advanced material applications, potentially useful in smart drug delivery systems (Lee et al., 2014).
  • Preparation and release behavior of poly(methyl methacrylate-co-methacrylic acid)-based electrospun nanofibrous mats loaded with doxorubicin: Examines the use of polymeric nanofibers for controlled drug release, particularly for cancer treatment, demonstrating the versatility of poly(methyl methacrylate-co-methacrylic acid) in pharmaceutical applications (López-Muñoz et al., 2023).

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Kateřina Dvořáčková et al.
Medicina (Kaunas, Lithuania), 48(4), 192-202 (2012-07-28)
Eudragit® NM was investigated as a matrix former in combination with microcrystalline cellulose as an insoluble filler for preparing controlled-release tablets containing model drugs with different solubility. Three sets of matrix tablets differing in the drug-to-filler ratio (1:1, 2:1, and
Rouslan I Moustafine et al.
International journal of pharmaceutics, 439(1-2), 17-21 (2012-10-09)
Interpolymer interactions between the countercharged methacrylate copolymers Eudragit(®) RL 30D (polycation) and Eudragit(®) FS 30D (polyanion), were investigated in conditions mimicking the gastrointestinal environment. The formation of inter-macromolecular ionic bonds between Eudragit(®) RL 30D and Eudragit(®) FS 30D was investigated
Katia P Seremeta et al.
Colloids and surfaces. B, Biointerfaces, 102, 441-449 (2012-09-27)
The design of simple and scalable drug delivery systems to target the central nervous system (CNS) could represent a breakthrough in the addressment of the HIV-associated neuropathogenesis. The intranasal (i.n.) route represents a minimally invasive strategy to surpass the blood-brain
Huasheng Yang et al.
Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 36(11), 1427-1430 (2012-07-12)
Using Apocynum venetum as a model drug to prepare pulsed-release tablets based on diffusion, swelling, osmotic pressure mechanism and to evaluate the release characteristics. The pulsatile release tablets were prepared by film coating methods using HPMC E5 and Eudragit The
Pravin K Pawar et al.
Acta pharmaceutica (Zagreb, Croatia), 62(1), 93-104 (2012-04-05)
The objective of the present investigation was to prepare and evaluate ocular inserts of moxifloxacin. An ocular insert was made from an aqueous dispersion of moxifloxacin, sodium alginate, polyvinyl alcohol, and dibutyl phthalate by the film casting method. The ocular

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