- New approach for the synthesis of isoxazoline-N-oxides.
New approach for the synthesis of isoxazoline-N-oxides.
Organic letters (2003-12-05)
Roman A Kunetsky, Alexander D Dilman, Sema L Ioffe, Marina I Struchkova, Yury A Strelenko, Vladimir A Tartakovsky
PMID14653704
摘要
A strategy for the synthesis of isoxazoline-N-oxides (cyclic five-membered nitronates) from primary nitro compounds and olefins is described. The key step of the process involves 1,3-dipolar cycloaddition of corresponding 1-bromosilyl nitronates with alkenes. [reaction: see text]
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