- Crosslinking with diacrylylpiperazine (PIP) reduces activation of complement by polyacrylamide microcapsules.
Crosslinking with diacrylylpiperazine (PIP) reduces activation of complement by polyacrylamide microcapsules.
Biomaterials, artificial cells, and immobilization biotechnology : official journal of the International Society for Artificial Cells and Immobilization Biotechnology (1991-01-01)
B Dupuy, H Gin, C Cadic, A Baquey, C Baquey, D Ducassou
PMID1810401
摘要
Activation of the complement system in vitro by a series of microcapsules based on polylysine, alginate or polyacrylamide was determined. Least activation was observed with microcapsules whose outer layer was composed of polyacrylamide. Activation was further reduced using diacrylylpiperazine instead of bisacrylamide as crosslinker.