- Pathoimmunological analyses of fatal E11 infection in premature infants.
Pathoimmunological analyses of fatal E11 infection in premature infants.
Frontiers in cellular and infection microbiology (2024-07-24)
Wei Luo, Lixia Wang, Zhengrong Chen, Ming Liu, Yixue Zhao, Yucan Wu, Bing Huang, Ping Wang
PMID39045132
摘要
E11 causes acute fulminant hepatitis in newborns. We investigated the pathological changes of different tissues from premature male twins who died due to E11 infection. The E11 expression level was higher in the liver than in other tissues. IP10 was upregulated in liver tissue in the patient group, and might be regulated by IFNAR and IRF7, whereas IFNα was regulated by IFNAR or IRF5.
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