- Morpholine catalyzed direct C3 alkenylation of indoles with α,β-unsaturated aldehydes.
Morpholine catalyzed direct C3 alkenylation of indoles with α,β-unsaturated aldehydes.
Chemical communications (Cambridge, England) (2011-06-21)
Shi-Kai Xiang, Bo Zhang, Li-He Zhang, Yuxin Cui, Ning Jiao
PMID21687862
摘要
Organocatalytic direct C3 alkenylation of indoles has been developed. Simple and readily available morpholine trifluoroacetic acid salt is employed as an efficient catalyst in this oxidative dehydrogenative reaction. Simplicity and practicality constitute the most attractive advantages of this reaction.