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重要文件

D9288

Sigma-Aldrich

1,6-二硝基芘

~60% (TLC)

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About This Item

經驗公式(希爾表示法):
C16H8N2O4
CAS號碼:
分子量::
292.25
MDL號碼:
分類程式碼代碼:
12352100
PubChem物質ID:

濃度

~60% (TLC)

mp

>300 °C (lit.)

儲存溫度

−20°C

SMILES 字串

[O-][N+](=O)c1ccc2ccc3c(ccc4ccc1c2c34)[N+]([O-])=O

InChI

1S/C16H8N2O4/c19-17(20)13-8-4-10-2-6-12-14(18(21)22)7-3-9-1-5-11(13)16(10)15(9)12/h1-8H

InChI 密鑰

GUXACCKTQWVTLG-UHFFFAOYSA-N

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象形圖

Health hazard

訊號詞

Danger

危險聲明

危險分類

Carc. 1B

儲存類別代碼

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type P3 (EN 143) respirator cartridges


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分析證明 (COA)

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Akiko H Hashimoto et al.
Environmental and molecular mutagenesis, 47(4), 277-283 (2006-02-21)
1,6-Dinitropyrene (1,6-DNP) is a ubiquitous airborne pollutant found in diesel exhaust. In this study, mutagenesis was examined in the lungs of gpt-delta transgenic mice after intratracheal instillation of 0-0.1 mg 1,6-DNP. In addition, the 1,6-DNP-induced gpt mutation spectrum was compared
B A Smith et al.
Mutation research, 379(1), 61-68 (1997-10-23)
Direct pulmonary instillation of 1,6-dinitropyrene (DNP) into male Fischer 344 rats results in a dose-dependent induction of lung tumors and 6-thioguanine-resistant (TGr) T-lymphocytes. The treatment also results in DNP binding to dG in the lung and in T-lymphocytes. In the
Nitroarenes (selected) 1,6-dinitropyrene.
Report on carcinogens : carcinogen profiles, 11, III186-III187 (2004-01-01)
Ning Tang et al.
Analytical sciences : the international journal of the Japan Society for Analytical Chemistry, 19(2), 249-253 (2003-03-01)
An automatic HPLC system for analyzing nitropolycyclic aromatic hydrocarbons (NPAHs, nitroarenes) in airborne particulates was previously described (Anal. Chim. Acta, 2001, 445, 20). Some problems with this system were that it generated a peak originating from an ascorbic acid solution
I B Lambert et al.
Mutagenesis, 13(1), 9-18 (1998-03-10)
We have examined the mutational specificity of 1-nitroso-6-nitropyrene (1,6-NONP), an activated metabolite of the carcinogen 1,6-dinitropyrene, in the lacI gene of Escherichia coli strains which are deficient in nucleotide excision repair (strain NR6113, delta uvrB; strain CM6114, delta uvrB, plasmid

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