AB15520

Anti-Neuronal pentraxin 2 Antibody

Chemicon^®, from rabbit

• 同義詞: NPX2
• 分類程式碼代碼: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

屬性

• 生物源: rabbit
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 物種活性: mouse
• 製造商／商標名: Chemicon^®
• 技術: ELISA: suitable; western blot: suitable
• NCBI登錄號: NM_002523.1
• UniProt登錄號: P47972
• 運輸包裝: dry ice
• 目標翻譯後修改: unmodified
• 基因資訊: mouse ... Morc3(338467)

描述

一般說明

Neuronal Pentraxins: A new family of putative integral membrane pentraxins or Neuronal pentraxins identified through interaction with a presynaptic snake venom toxin taipoxin. NPX1, NPX2 and NPXR (Neuronal Pentraxin Receptor), the three neuronal pentraxins represent a novel neuronal uptake pathway that may function during synapse formation and remodeling. The N-terminal half of neuronal pentraxins are 20-30% identical to previously identified pentraxins (CRP and SAP), the three neuronal pentraxins are 50% identical to each other and are significantly larger than the classical pentraxins (>50 versus 30kDa), suggesting that they may have additional novel functions. NPX2 (Neuronal Pentraxin 2), 429aa in mouse, 432 in rat and 431 in human (chr 7q21), mainly expressed in brain, pancrease, liver and testis. It is likely to play role in the modification of cellular properties that underlie long-term plasticity. NPX1, NPX2 has potential N-linked glycosylation sites.

特異性

Other species have not yet been tested. The immunogen sequence is 100% conserved in rat, and 94% in human NPX2 and 82% in guinea pig apexin precursor P50.

免疫原

Synthetic peptide near the N-terminus of mouse NPX2

應用

Detect Neuronal pentraxin 2 using this Anti-Neuronal pentraxin 2 Antibody validated for use in ELISA & WB.

Research Category
Neuroscience

Research Sub Category
Synapse & Synaptic Biology

Western blot: 1-10 µg/mL using ECL.
Immunohistochemistry: Not tested. It is recommended that the antibody be tried at 2-20 µg/mL
ELISA: 1:10,000-1:100,000 using 50-100 ng of control peptide/well.
Optimal working dilutions must be determined by end user.

外觀

ImmunoAffinity Purified

Format: Purified

Liquid in 100 mM Tris, pH 7.5 and 0.1% BSA.

儲存和穩定性

Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.

法律資訊

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全資訊

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 2
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable