424048

2,6-二喹啉二醇

• 同義詞: 2,6-Dihydroxyquinoline, 6-Hydroxycarbostyril
• 經驗公式（希爾表示法）: C₉H₇NO₂
• CAS號碼: 19315-93-6
• 分子量：: 161.16
• MDL號碼: MFCD00239446
• 分類程式碼代碼: 12352100
• PubChem物質ID: 24866548
• NACRES: NA.22

屬性

• mp: >300 °C (lit.)
• SMILES 字串: Oc1ccc2nc(O)ccc2c1
• InChI: 1S/C9H7NO2/c11-7-2-3-8-6(5-7)1-4-9(12)10-8/h1-5,11H,(H,10,12)
• InChI 密鑰: AQLYZDRHNHZHIS-UHFFFAOYSA-N

描述

一般說明

2,6-Quinolinediol is a substituted quinoline compound.[1] It has been prepared starting from 6-methoxyquinoline.[2] It has been reported to be one of the UV-absorbing compounds (UAC) found in cow milk.[1]

應用

2,6-Quinolinediol may be used as a test compound to investigate the carcinogenicity of the naturally occurring quinoline metabolite of tryptophan. The study was conducted by suspending tryptophan metabolites in cholesterol pellets, followed by the surgical implantation of the pellets into the mice bladder.[3] It may be used as a reactant in the synthesis of 2-chloro-6-quinolinol by reacting with POCl₃ (phosphorus oxychloride).[4]

Reactant involved in synthesis of:

• (Benzyloxy)methylquinolinone derivatives for use as PDE3 inhibitors
• Substances related to cilostazol
• 2,6-Quinolinyl derivatives for use as VLA-4 / VCAM-1 antagonists

安全資訊

• 象形圖: GHS07
• 訊號詞: Warning
• 危險聲明: H315,H319,H335
• 防範說明: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• 危險分類: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• 標靶器官: Respiratory system
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Gloves