Therapeutic Antibody Development
Tools to accelerate preclinical studies in antibody
drug development.
Robust preclinical methods are crucial for evaluation of potential antibody drugs, ensuring that time, money, and effort are spent on the most promising candidates with greatest therapeutic potential. Recent advances in preclinical modeling and multi-parameter analysis have significantly improved the rigor of experimental evaluation of lead antibody candidates. Our products provide more biologically relevant models and enable more comprehensive assessment to accelerate therapeutic antibody development.
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Preclinical Efficacy and Safety
In vitro Models
Cell-based assays, 2D, and 3D models offer invaluable advantages to early drug discovery, providing cost-effective and efficient methods for identifying lead candidates with high affinity, high specificity, and low toxicity. The advent of next-generation, advanced cell culture models has transformed drug discovery and development, providing tools that more precisely replicate the in vivo environment and more accurately predict physiological response. Such models have become crucial for better evaluating the efficacy and toxicology of drugs. By measuring various cellular processes, the most promising candidates can be selected for further development, accelerating drug discovery while shedding comprehensive light on a drug candidate’s potential effects. We provide numerous cellular models, assays, instruments, and reagents to support your drug development needs.
PK/PD and Immunogenicity
Comprehensively analyze preclinical response with MILLIPLEX® multiplexing biomarker assays. Based on Luminex® xMAP® technology, MILLIPLEX® assays enable precise, multiparametric analysis. Our wide-ranging, industry leading MILLIPLEX® panels include kits to measure cytokines, chemokines, growth factors, immunoglobulins, and more. These panels enable quantitative investigation of the modulation and expression of dozens of analytes simultaneously, with speed and sensitivity. For highest sensitivity, evaluate biotherapeutic PK/PD and immunogenicity using SMC® technology for detection at the single molecule level.
Related Categories
Human iPSC-derived and patient-derived organoids for advanced cell culture.
Products for live cell imaging, cell health, and cell migration and invasion.
Featuring high-performance Millipore® membranes in a wide variety of formats.
Promoting natural, multidimensional growth for more relevant in vitro models.
Comprehensive mass spectrometry reagents to cover your complete workflow.
Analyze preclinical response with MILLIPLEX® multiplexing biomarker assays.
SMC® high sensitivity technology for sensitivity down to the single molecule.
Related Resources
- Transcriptomics
Comprehensively profile infection, disease, or immune response with MULTI-seq analysis.
- Webinar: Metabolomics
Optimize mass spectrometry metabolomics applications.
- MILLIPLEX® Multiplex Assays for Immunology
Profile more immune biomarkers, faster.
- High-Sensitivity Immunoassays in PK/PD Studies
SMC® ultrasensitive immunoassays for preclinical work.
- High Sensitivity Immunogenicity Assays
See how SMC® technology makes detecting anti-drug antibodies easier.
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