UPF1
UPF1 regulator of nonsense transcripts homolog (yeast)
同義詞:
HUPF1, NORF1, RENT1, pNORF1, smg-2
物種:
Human UPF1 (5976), Mouse Upf1 (19704), Rat Upf1 (684558), Horse UPF1 (100071059), cow UPF1 (532933), Zebrafish upf1 (406783), chicken UPF1 (420119), domestic cat UPF1 (101096043), naked mole-rat Upf1 (101704366), fruit fly Upf1 (32153) ...更多
UniProtKB ID:
基因 ID:
- Human(5976) Summary: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein is located only in the cytoplasm. When translation ends, it interacts with the protein that is a functional homolog of yeast Upf2p to trigger mRNA decapping. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
- Mouse(19704) UPF1 regulator of nonsense transcripts homolog (yeast)
- Rat(684558) UPF1 regulator of nonsense transcripts homolog (yeast)
- Horse(100071059) UPF1 regulator of nonsense transcripts homolog (yeast)
- cow(532933) UPF1 regulator of nonsense transcripts homolog (yeast)
- Zebrafish(406783) upf1 regulator of nonsense transcripts homolog (yeast)
- chicken(420119) UPF1 regulator of nonsense transcripts homolog (yeast)
- domestic cat(101096043) UPF1 regulator of nonsense transcripts homolog (yeast)
- naked mole-rat(101704366) UPF1 regulator of nonsense transcripts homolog (yeast)
- fruit fly(32153) CG1559 gene product from transcript CG1559-RA
- sheep(101107598) UPF1 regulator of nonsense transcripts homolog (yeast)
- dog(476664) UPF1 regulator of nonsense transcripts homolog (yeast)
- domestic guinea pig(100713813) UPF1 regulator of nonsense transcripts homolog (yeast)
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Antibodies
產品編號
描述
物種活性
應用
抗-磷酸化-Upf1（Ser1127）抗体, from rabbit, purified by affinity chromatography,
物種活性
bovine, chicken, human, mouse, rat, yeast, zebrafish
應用
immunoprecipitation (IP)
western blot
western blot
Monoclonal Anti-UPF1 antibody produced in mouse, clone 4G3, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
western blot
Goat anti-RENT1 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
物種活性
human, mouse
應用
immunoprecipitation (IP)
western blot
western blot
Anti-Smg-2 (N-term) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human
應用
ELISA
western blot
western blot