RASD1
RAS, dexamethasone-induced 1
同義詞:
AGS1, DEXRAS1, MGC:26290
物種:
Human RASD1 (51655), Mouse Rasd1 (19416), Rat Rasd1 (64455), chicken RASD1 (416507), Zebrafish rasd1 (393504), naked mole-rat Rasd1 (101707211), dog RASD1 (489542), sheep RASD1 (100302075), domestic cat RASD1 (101080588), cow RASD1 (507449)
UniProtKB ID:
基因 ID:
- Human(51655) Summary: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2011]
- Mouse(19416) RAS, dexamethasone-induced 1
- Rat(64455) RAS, dexamethasone-induced 1
- chicken(416507) RAS, dexamethasone-induced 1
- Zebrafish(393504) RAS, dexamethasone-induced 1
- naked mole-rat(101707211) RAS, dexamethasone-induced 1
- dog(489542) RAS, dexamethasone-induced 1
- sheep(100302075) RAS, dexamethasone-induced 1
- domestic cat(101080588) RAS, dexamethasone-induced 1
- cow(507449) RAS, dexamethasone-induced 1
- domestic guinea pig(100730809) RAS, dexamethasone-induced 1
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