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Merck

PTGS2

prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

同義詞:
COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2
物種:
UniProtKB ID:
基因 ID:
  • Human(5743) Summary: Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes the inducible isozyme. It is regulated by specific stimulatory events, suggesting that it is responsible for the prostanoid biosynthesis involved in inflammation and mitogenesis. [provided by RefSeq, Feb 2009]
  • Mouse(19225) prostaglandin-endoperoxide synthase 2
  • Rat(29527) prostaglandin-endoperoxide synthase 2
  • Goat(100860905) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • cow(282023) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Horse(791253) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic cat(100126581) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • dog(442942) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • Domestic Rabbit(100009248) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • sheep(443460) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • naked mole-rat(101704771) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • chicken(396451) prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
  • domestic guinea pig(100135607) prostaglandin-endoperoxide synthase 2

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ELISA

產品編號
描述
物種
人COX-2 ELISA试剂盒, for cell culture supernatants, plasma, and serum samples,
物種
human

Antibodies

產品編號
描述
物種活性
應用
COX-2 (SP21) Rabbit Monoclonal Antibody, ,
物種活性
human
應用
immunohistochemistry
抗-COX2 兔抗, affinity isolated antibody,
物種活性
human
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-COX-2 antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM348, purified immunoglobulin,
物種活性
human
應用
immunohistochemistry
Anti-Cyclooxygenase-2 Antibody, Chemicon®, from rabbit,
物種活性
bovine, human, mouse, sheep
應用
ELISA
western blot
Anti-COX2 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP21, tissue culture supernatant,
物種活性
bovine, dog, frog, human, mouse, rat
應用
immunohistochemistry

Small Molecule - Blocker

產品編號
描述
物種
N--甲苯磺酰基-L-苯基乙基氯甲基酮, ≥97% (TLC), powder,
物種
human

Small Molecule - Inhibitor

產品編號
描述
物種
卡洛芬, ≥97% (HPLC),
物種
human
Aceclofenac, ≥98% (HPLC),
物種
human
塞来昔布, Pharmaceutical Secondary Standard; Certified Reference Material,
物種
human
塞来昔布, United States Pharmacopeia (USP) Reference Standard,
物種
human
依托考昔, VETRANAL®, analytical standard,
物種
human

Proteins

產品編號
描述
物種
环氧化酶 2 人, ≥70% (SDS-PAGE), recombinant, expressed in insect cells, aqueous solution, ≥8000 units/mg protein,
物種
human

esiRNA

產品編號
描述
物種
MISSION® esiRNA, targeting mouse Ptgs2,
物種
mouse
MISSION® esiRNA, targeting human PTGS2,
物種
human