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Merck

PTGIS

prostaglandin I2 (prostacyclin) synthase

同義詞:
CYP8, CYP8A1, PGIS, PTGI
物種:
UniProtKB ID:
基因 ID:
  • Human(5740) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis. [provided by RefSeq, Jul 2008]
  • Mouse(19223) prostaglandin I2 (prostacyclin) synthase
  • Rat(25527) prostaglandin I2 (prostacyclin) synthase
  • dog(485919) prostaglandin I2 (prostacyclin) synthase
  • Goat(100860894) prostaglandin I2 (prostacyclin) synthase
  • cow(282021) prostaglandin I2 (prostacyclin) synthase
  • domestic guinea pig(100734621) prostaglandin I2 (prostacyclin) synthase
  • Zebrafish(559148) prostaglandin I2 (prostacyclin) synthase
  • sheep(101116418) prostaglandin I2 (prostacyclin) synthase
  • Horse(100071412) prostaglandin I2 (prostacyclin) synthase
  • naked mole-rat(101700601) prostaglandin I2 (prostacyclin) synthase
  • domestic cat(101082050) prostaglandin I2 (prostacyclin) synthase

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Antibodies

產品編號
描述
物種活性
應用
Anti-PTGIS antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, human, mouse, rat
應用
western blot

Small Molecule - Ligand

產品編號
描述
物種
保泰松, ,
物種
human