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Merck

PRKCE

protein kinase C, epsilon

同義詞:
PKCE, nPKC-epsilon
物種:
Human PRKCE (5581), Mouse Prkce (18754), Rat Prkce (29340), chicken PRKCE (421409), domestic cat PRKCE (101100958), dog PRKCE (609934), cow PRKCE (507041), Horse PRKCE (100053394), Domestic Rabbit PRKCE (100009103), sheep PRKCE (101110314) ...更多
UniProtKB ID:
Q02156, B0LPH7, Q32MQ3, Q53SL4, Q53SM5, Q9UE81
基因 ID:
  • Human(5581) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This kinase has been shown to be involved in many different cellular functions, such as neuron channel activation, apoptosis, cardioprotection from ischemia, heat shock response, as well as insulin exocytosis. Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior. [provided by RefSeq, Jul 2008]
  • Mouse(18754) protein kinase C, epsilon
  • Rat(29340) protein kinase C, epsilon
  • chicken(421409) protein kinase C, epsilon
  • domestic cat(101100958) protein kinase C, epsilon
  • dog(609934) protein kinase C, epsilon
  • cow(507041) protein kinase C, epsilon
  • Horse(100053394) protein kinase C, epsilon
  • Domestic Rabbit(100009103) protein kinase C, epsilon
  • sheep(101110314) protein kinase C, epsilon
  • naked mole-rat(101700837) protein kinase C, epsilon
  • domestic guinea pig(100721814) protein kinase C, epsilon

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Small Molecule - Agonist

產品編號
描述
物種
O1008
油酸, ≥99% (GC),
物種
human

Antibodies

產品編號
描述
物種活性
應用
06-991
Anti-PKCε Antibody, Upstate®, from rabbit,
物種活性
human, mouse, rat
應用
immunohistochemistry
immunoprecipitation (IP)
western blot
06-821-I
Anti-phospho-PKCepsilon Antibody (Ser729), from rabbit, purified by affinity chromatography,
物種活性
human, mouse, rat
應用
western blot
SAB4502367
Anti-PKC ε antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
SAB4504099
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
I7016
H-7 dihydrochloride, ≥98% (HPLC),
物種
human
T9262
他莫昔芬 柠檬酸盐, ≥99%,
物種
human
O1008
油酸, ≥99% (GC),
物種
human
U6508
UCN-01, ≥97% (HPLC), powder,
物種
human
SML0428
GSK690693, ≥98% (HPLC),
物種
human

Proteins

產品編號
描述
物種
14-518
PKCε 蛋白（活性，10 µg）, Active, N-terminal His6-tagged, recombinant PKCε, amino acids 2-end. For use in Kinase Assays.,
物種
human
SRP5067
PKC ε , active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human