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Merck

PRKACA

protein kinase, cAMP-dependent, catalytic, alpha

同義詞:
PKACA
物種:
UniProtKB ID:
基因 ID:
  • Human(5566) Summary: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(18747) protein kinase, cAMP dependent, catalytic, alpha
  • Rat(25636) protein kinase, cAMP-dependent, catalytic, alpha
  • naked mole-rat(101707235) protein kinase, cAMP-dependent, catalytic, alpha
  • sheep(443094) protein kinase, cAMP-dependent, catalytic, alpha
  • domestic guinea pig(100735694) protein kinase, cAMP-dependent, catalytic, alpha
  • dog(403556) protein kinase, cAMP-dependent, catalytic, alpha
  • Horse(100064302) protein kinase, cAMP-dependent, catalytic, alpha
  • cow(282322) protein kinase, cAMP-dependent, catalytic, alpha
  • domestic cat(101090494) protein kinase, cAMP-dependent, catalytic, alpha

Custom & Knockdown Gene Products

Antibodies

產品編號
描述
物種活性
應用
Anti-PKA α antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-PKA α/β CAT (pThr197) antibody produced in rabbit, affinity isolated antibody,
物種活性
human, mouse
應用
immunohistochemistry
western blot
抗-磷酸化-PKA CAT (pThr197) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence

immunohistochemistry

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
Protein Kinase A inhibitor fragment 14-22, myristoylated trifluoroacetate salt, ≥90% (HPLC), lyophilized powder,
物種
mouse, rat, human
酪氨酸激酶抑制剂A9, solid,
物種
mouse, human
腺嘌呤, ≥99%,
物種
human, rat, mouse
腺嘌呤, BioReagent, suitable for cell culture,
物種
human, rat, mouse
腺嘌呤, BioReagent, suitable for plant cell culture, ≥99%,
物種
human, rat, mouse

Proteins

產品編號
描述
物種
PKA蛋白,重组,10 µg, Recombinant human full length PKA, catalytic subunit type alpha, untagged, for use in Kinase Assays.,
物種
Protein Kinase A catalytic subunit human, >90% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution,
物種
human
蛋白激酶A 来源于牛心脏, ≥0.8 units/μg protein, lyophilized powder,
物種
cow