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Merck

PRELP

proline/arginine-rich end leucine-rich repeat protein

同義詞:
MST161, MSTP161, SLRR2A
物種:
Human PRELP (5549), Mouse Prelp (116847), Rat Prelp (84400), domestic cat PRELP (101101284), naked mole-rat Prelp (101701329), dog PRELP (488561), cow PRELP (282000), chicken PRELP (419933), sheep PRELP (101111470), Zebrafish prelp (100144408)
UniProtKB ID:
P51888, Q6FG38
基因 ID:
  • Human(5549) Summary: The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
  • Mouse(116847) proline arginine-rich end leucine-rich repeat
  • Rat(84400) proline/arginine-rich end leucine-rich repeat protein
  • domestic cat(101101284) proline/arginine-rich end leucine-rich repeat protein
  • naked mole-rat(101701329) proline/arginine-rich end leucine-rich repeat protein
  • dog(488561) proline/arginine-rich end leucine-rich repeat protein
  • cow(282000) proline/arginine-rich end leucine-rich repeat protein
  • chicken(419933) proline/arginine-rich end leucine-rich repeat protein
  • sheep(101111470) proline/arginine-rich end leucine-rich repeat protein
  • Zebrafish(100144408) proline/arginine-rich end leucine-rich repeat protein
  • domestic guinea pig(100726579) proline/arginine-rich end leucine-rich repeat protein

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