POT1
protection of telomeres 1
同義詞:
HPOT1
物種:
Human POT1 (25913), Rat Pot1 (500054), chicken POT1 (404538), Zebrafish pot1 (566847), domestic guinea pig Pot1 (100725051), naked mole-rat Pot1 (101698900), sheep POT1 (101107695), cow POT1 (511292), Horse POT1 (100071610), domestic cat POT1 (101097225)
UniProtKB ID:
基因 ID:
- Human(25913) Summary: This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
- Rat(500054) protection of telomeres 1
- chicken(404538) protection of telomeres 1 homolog (S. pombe)
- Zebrafish(566847) protection of telomeres 1 homolog
- domestic guinea pig(100725051) protection of telomeres 1
- naked mole-rat(101698900) protection of telomeres 1
- sheep(101107695) protection of telomeres 1 homolog (S. pombe)
- cow(511292) protection of telomeres 1
- Horse(100071610) protection of telomeres 1 homolog (S. pombe)
- domestic cat(101097225) protection of telomeres 1 homolog (S. pombe)
- dog(609119) protection of telomeres 1 homolog (S. pombe)
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