PIK3R5
phosphoinositide-3-kinase, regulatory subunit 5
同義詞:
F730038I15Rik, FOAP-2, P101-PI3K, p101
物種:
Human PIK3R5 (23533), Mouse Pik3r5 (320207), Rat Pik3r5 (497931), cow PIK3R5 (614838), Domestic Rabbit PIK3R5 (100337757), domestic cat PIK3R5 (101082354), dog PIK3R5 (612805), domestic guinea pig Pik3r5 (100729793), chicken PIK3R5 (417319), Zebrafish pik3r5 (323588) ...更多
UniProtKB ID:
基因 ID:
- Human(23533) Summary: Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found. [provided by RefSeq, Oct 2011]
- Mouse(320207) phosphoinositide-3-kinase, regulatory subunit 5, p101
- Rat(497931) phosphoinositide-3-kinase, regulatory subunit 5
- cow(614838) phosphoinositide-3-kinase, regulatory subunit 5
- Domestic Rabbit(100337757) phosphoinositide-3-kinase, regulatory subunit 5
- domestic cat(101082354) phosphoinositide-3-kinase, regulatory subunit 5
- dog(612805) phosphoinositide-3-kinase, regulatory subunit 5
- domestic guinea pig(100729793) phosphoinositide-3-kinase, regulatory subunit 5
- chicken(417319) phosphoinositide 3-kinase regulatory subunit 5
- Zebrafish(323588) phosphoinositide-3-kinase, regulatory subunit 5
- naked mole-rat(101721762) phosphoinositide-3-kinase, regulatory subunit 5
- sheep(101109983) phosphoinositide-3-kinase, regulatory subunit 5
- Horse(100062810) phosphoinositide-3-kinase, regulatory subunit 5
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