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Merck

PDE1A

phosphodiesterase 1A, calmodulin-dependent

同義詞:
CAM-PDE-1A, HCAM-1, HCAM1, HSPDE1A
物種:
Human PDE1A (5136), Mouse Pde1a (18573), Rat Pde1a (81529), chicken PDE1A (424116), Zebrafish pde1a (564465), domestic cat PDE1A (101083101), dog PDE1A (403652), naked mole-rat Pde1a (101712147), sheep PDE1A (101119369), Domestic Rabbit PDE1A (100346878) ...更多
UniProtKB ID:
P54750, D3DPG5, Q86VZ0, Q9C0K8, Q9C0K9, Q9C0L0, Q9C0L1, Q9C0L2
基因 ID:
  • Human(5136) Summary: Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109]
  • Mouse(18573) phosphodiesterase 1A, calmodulin-dependent
  • Rat(81529) phosphodiesterase 1A, calmodulin-dependent
  • chicken(424116) phosphodiesterase 1A, calmodulin-dependent
  • Zebrafish(564465) phosphodiesterase 1A, calmodulin-dependent
  • domestic cat(101083101) phosphodiesterase 1A, calmodulin-dependent
  • dog(403652) phosphodiesterase 1A, calmodulin-dependent
  • naked mole-rat(101712147) phosphodiesterase 1A, calmodulin-dependent
  • sheep(101119369) phosphodiesterase 1A, calmodulin-dependent
  • Domestic Rabbit(100346878) phosphodiesterase 1A, calmodulin-dependent
  • cow(281969) phosphodiesterase 1A, calmodulin-dependent
  • Horse(100054082) phosphodiesterase 1A, calmodulin-dependent
  • domestic guinea pig(100527956) phosphodiesterase 1A, calmodulin-dependent

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Small Molecule - Inhibitor

產品編號
描述
物種
M2547
8-Methoxymethyl-3-isobutyl-1-methylxanthine, ≥98%,
物種
human
V6383
长春西汀, ≥98%, solid,
物種
human
1220506
双嘧达莫, United States Pharmacopeia (USP) Reference Standard,
物種
human
BP131
双嘧达莫, British Pharmacopoeia (BP) Reference Standard,
物種
human
Y0000802
双嘧达莫, European Pharmacopoeia (EP) Reference Standard,
物種
human

Proteins

產品編號
描述
物種
SRP0257
PDE1A Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
物種
human