P4HB
prolyl 4-hydroxylase, beta polypeptide
同義詞:
DSI, ERBA2L, GIT, P4Hbeta, PDI, PDIA1, PHDB, PO4DB, PO4HB, PROHB
物種:
Human P4HB (5034), Mouse P4hb (18453), Rat P4hb (25506), sheep P4HB (100135700), Zebrafish p4hb (406673), sheep P4HB (101115218), chicken P4HB (374091), naked mole-rat P4hb (101712215), cow P4HB (281373), dog P4HB (483369) ...更多
UniProtKB ID:
基因 ID:
- Human(5034) Summary: This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008]
- Mouse(18453) prolyl 4-hydroxylase, beta polypeptide
- Rat(25506) prolyl 4-hydroxylase, beta polypeptide
- sheep(100135700) prolyl 4-hydroxylase, beta polypeptide
- Zebrafish(406673) procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide
- sheep(101115218) prolyl 4-hydroxylase, beta polypeptide
- chicken(374091) prolyl 4-hydroxylase, beta polypeptide
- naked mole-rat(101712215) prolyl 4-hydroxylase, beta polypeptide
- cow(281373) prolyl 4-hydroxylase, beta polypeptide
- dog(483369) prolyl 4-hydroxylase, beta polypeptide
- domestic guinea pig(100733944) prolyl 4-hydroxylase, beta polypeptide
- Domestic Rabbit(100328595) prolyl 4-hydroxylase, beta polypeptide
- domestic cat(101099917) prolyl 4-hydroxylase, beta polypeptide
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Antibodies
產品編號
描述
物種活性
應用
Anti-P4HB (AB2) antibody produced in rabbit, affinity isolated antibody,
物種活性
bovine, dog, horse, human, mouse, pig, rabbit, rat
應用
immunohistochemistry
western blot
western blot
Anti-Protein Disulfide Isomerase (DL-11) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
human, mouse, rat
應用
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Protein Disulfide Isomerase antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
bovine, human, mouse, rat
應用
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Protein Disulfide Isomerase (MD-12) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
物種活性
bovine, human, mouse, rat
應用
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
產品編號
描述
物種