OPTN
optineurin
同義詞:
ALS12, FIP2, GLC1E, HIP7, HYPL, NRP, TFIIIA-INTP
物種:
Human OPTN (10133), Mouse Optn (71648), Rat Optn (246294), domestic guinea pig Optn (100722896), naked mole-rat Optn (101725616), domestic cat OPTN (101087414), cow OPTN (534150), sheep OPTN (101106703), chicken OPTN (374079), dog OPTN (478003)
UniProtKB ID:
基因 ID:
- Human(10133) Summary: This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
- Mouse(71648) optineurin
- Rat(246294) optineurin
- domestic guinea pig(100722896) optineurin
- naked mole-rat(101725616) optineurin
- domestic cat(101087414) optineurin
- cow(534150) optineurin
- sheep(101106703) optineurin
- chicken(374079) optineurin
- dog(478003) optineurin
- Zebrafish(336159) optineurin
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Antibodies
產品編號
描述
物種活性
應用
Anti-OPTN antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
物種活性
human
應用
immunofluorescence
western blot
western blot
Anti-OPTN antibody produced in rabbit, affinity isolated antibody,
物種活性
dog, guinea pig, horse, human, mouse, rabbit, rat
應用
western blot
Anti-OPTN (ab2) antibody produced in rabbit, affinity isolated antibody,
物種活性
guinea pig, human
應用
western blot