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NXF3

nuclear RNA export factor 3

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基因 ID:
  • Human(56000) Summary: This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. [provided by RefSeq, Jul 2008]
  • Mouse(245610) nuclear RNA export factor 3
  • Rat(302591) nuclear RNA export factor 3
  • dog(491441) nuclear RNA export factor 3
  • Horse(100060140) nuclear RNA export factor 3
  • Horse(100060240) nuclear RNA export factor 3
  • cow(523530) nuclear RNA export factor 3
  • cow(785244) nuclear RNA export factor 3
  • cow(615581) nuclear RNA export factor 3
  • fruit fly(317878) Nuclear export factor 3

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