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Merck

NTRK1

neurotrophic tyrosine kinase, receptor, type 1

同義詞:
MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA
物種:
UniProtKB ID:
基因 ID:
  • Human(4914) Summary: This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
  • Mouse(18211) neurotrophic tyrosine kinase, receptor, type 1
  • Rat(59109) neurotrophic tyrosine kinase, receptor, type 1
  • chicken(396337) neurotrophic tyrosine kinase, receptor, type 1
  • domestic cat(101081603) neurotrophic tyrosine kinase, receptor, type 1
  • domestic guinea pig(100725325) neurotrophic tyrosine kinase, receptor, type 1
  • naked mole-rat(101724441) neurotrophic tyrosine kinase, receptor, type 1
  • cow(353111) neurotrophic tyrosine kinase, receptor, type 1
  • sheep(101109763) neurotrophic tyrosine kinase, receptor, type 1
  • Domestic Rabbit(100354292) neurotrophic tyrosine kinase, receptor, type 1
  • Horse(100064594) neurotrophic tyrosine kinase, receptor, type 1
  • dog(490404) neurotrophic tyrosine kinase, receptor, type 1
  • Zebrafish(30546) neurotrophic tyrosine kinase, receptor, type 1

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Antibodies

產品編號
描述
物種活性
應用
抗-TrkA抗体, Upstate®, from rabbit,
物種活性
human, mouse, rat
應用
immunocytochemistry
immunoprecipitation (IP)

western blot
Anti-TrkA Antibody, clone 6B2, ascites fluid, clone 6B2, from mouse,
物種活性
human, rat
應用
immunocytochemistry
immunohistochemistry

western blot
Anti-phospho-TrkA (pTyr490) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human, mouse, rat
應用
immunocytochemistry
immunohistochemistry

immunoprecipitation (IP)

western blot

Small Molecule - Inhibitor

產品編號
描述
物種
K-252a, Ready Made Solution, from Nonomuraea longicatena, >98%,
物種
rat, human
K-252a, from Nonomuraea longicatena, ≥98% (HPLC),
物種
rat, human
Tyrphostin AG 879, 99% (HPLC),
物種
human