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Merck

MBP

myelin basic protein

同義詞:
物種:
UniProtKB ID:
基因 ID:
  • Human(4155) Summary: The protein encoded by the classic MBP gene is a major constituent of the myelin sheath of oligodendrocytes and Schwann cells in the nervous system. However, MBP-related transcripts are also present in the bone marrow and the immune system. These mRNAs arise from the long MBP gene (otherwise called 'Golli-MBP') that contains 3 additional exons located upstream of the classic MBP exons. Alternative splicing from the Golli and the MBP transcription start sites gives rise to 2 sets of MBP-related transcripts and gene products. The Golli mRNAs contain 3 exons unique to Golli-MBP, spliced in-frame to 1 or more MBP exons. They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence. The second family of transcripts contain only MBP exons and produce the well characterized myelin basic proteins. This complex gene structure is conserved among species suggesting that the MBP transcription unit is an integral part of the Golli transcription unit and that this arrangement is important for the function and/or regulation of these genes. [provided by RefSeq, Jul 2008]
  • Mouse(17196) myelin basic protein
  • Rat(24547) myelin basic protein
  • chicken(396217) myelin basic protein
  • domestic cat(101096421) myelin basic protein
  • dog(476160) myelin basic protein
  • sheep(101109407) myelin basic protein
  • cow(618684) myelin basic protein
  • naked mole-rat(101702488) myelin basic protein
  • domestic guinea pig(100731253) myelin basic protein

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Antibodies

產品編號
描述
物種活性
應用
抗-髓磷脂碱性蛋白小鼠单克隆抗体(SMI-99), liquid, clone SMI-99, Calbiochem®,
物種活性
guinea pig, mammals
應用
Monoclonal Anti-MBP antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2829, purified immunoglobulin, buffered aqueous glycerol solution,
物種活性
human, mouse, rat
應用
immunohistochemistry
western blot
抗-MBP, affinity isolated antibody,
物種活性
dog, guinea pig, horse, human, rabbit, rat
應用
western blot
Monoclonal Anti-Myelin Basic Protein (MBP) (36-50) antibody produced in rat, clone 14, tissue culture supernatant,
物種活性
chicken, horse, human
應用
ELISA
immunofluorescence

immunohistochemistry
单克隆抗-MBP 小鼠抗, Prestige Antibodies® Powered by Atlas Antibodies, clone CL2819, purified immunoglobulin, buffered aqueous glycerol solution,
物種活性
human, mouse, rat
應用
immunofluorescence
immunohistochemistry

western blot

Proteins

產品編號
描述
物種
髓鞘碱性蛋白 牛, ≥90% (SDS-PAGE), lyophilized powder, suitable for activity assay,
物種
cow
Myelin Basic Protein Antigen from human brain, ≥95% (SDS-PAGE),
物種
human
MBP,脱磷酸化, ,
物種
cow
MBP(髓磷脂碱性蛋白),牛,纯化, ,
物種
cow
髓鞘碱性蛋白 来源于天竺鼠大脑, ≥80% (SDS-PAGE), lyophilized powder, from guinea pig brain,
物種
domestic guinea pig