MAPK7
mitogen-activated protein kinase 7
同義詞:
BMK1, ERK4, ERK5, PRKM7
物種:
Human MAPK7 (5598), Mouse Mapk7 (23939), Rat Mapk7 (114509), Zebrafish mapk7 (541323), domestic cat MAPK7 (101097357), cow MAPK7 (537703), dog MAPK7 (489532), Domestic Rabbit MAPK7 (100338535), sheep MAPK7 (101110073), naked mole-rat Mapk7 (101726391)
UniProtKB ID:
基因 ID:
- Human(5598) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(23939) mitogen-activated protein kinase 7
- Rat(114509) mitogen-activated protein kinase 7
- Zebrafish(541323) mitogen-activated protein kinase 7
- domestic cat(101097357) mitogen-activated protein kinase 7
- cow(537703) mitogen-activated protein kinase 7
- dog(489532) mitogen-activated protein kinase 7
- Domestic Rabbit(100338535) mitogen-activated protein kinase 7
- sheep(101110073) mitogen-activated protein kinase 7
- naked mole-rat(101726391) mitogen-activated protein kinase 7
- domestic guinea pig(100728396) mitogen-activated protein kinase 7
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Antibodies
產品編號
描述
物種活性
應用
Anti-phospho-ERK5 (pThr218/pTyr220) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
物種活性
human
應用
Anti-ERK5 (big-MAPK, BMK1) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
物種活性
human, mouse
應用
microarray
western blot
western blot
抗磷酸化-BMK1/Erk5 (Thr218/Tyr220) 抗体, Upstate®, from rabbit,
物種活性
bovine, human, mouse, rat
應用
inhibition assay
western blot
western blot