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Merck

LCK

lymphocyte-specific protein tyrosine kinase

同義詞:
LSK, YT16, p56lck, pp58lck
物種:
Human LCK (3932), Mouse Lck (16818), Rat Lck (313050), chicken LCK (396460), Zebrafish lck (414333), domestic cat LCK (101098805), dog LCK (478151), Domestic Rabbit LCK (100349102), sheep LCK (100216439), cow LCK (508890) ...更多
UniProtKB ID:
P06239, D3DPP8, P07100, Q12850, Q13152, Q5TDH8, Q5TDH9, Q7RTZ3
基因 ID:
  • Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
  • Mouse(16818) lymphocyte protein tyrosine kinase
  • Rat(313050) lymphocyte-specific protein tyrosine kinase
  • chicken(396460) lymphocyte-specific protein tyrosine kinase
  • Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
  • domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
  • dog(478151) lymphocyte-specific protein tyrosine kinase
  • Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
  • sheep(100216439) lymphocyte-specific protein tyrosine kinase
  • cow(508890) lymphocyte-specific protein tyrosine kinase
  • Horse(100146139) lymphocyte-specific protein tyrosine kinase
  • naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
  • domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase

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Small Molecule - Antagonist

產品編號
描述
物種
536954
迷迭香酸, 96%,
物種
human
594687
α-六噻吩, ,
物種
human, rat

Antibodies

產品編號
描述
物種活性
應用
06-583
抗Lck抗体, Upstate®, from rabbit,
物種活性
human
應用
immunoprecipitation (IP)
western blot
SAB4300118
抗-磷酸-LCK (pTyr394) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
western blot
05-435
Anti-Lck Antibody, clone 3A5, clone 3A5, Upstate®, from mouse,
物種活性
human, mouse, rat
應用
immunoprecipitation (IP)
western blot
SAB4504657
抗-磷酸化-LCK (pSer59) 兔抗, affinity isolated antibody,
物種活性
human, mouse, rat
應用
ELISA
western blot
SAB2502039
Anti-LCK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
物種活性
bovine, canine, human, mouse, pig, rat
應用
ELISA
western blot

Small Molecule - Inhibitor

產品編號
描述
物種
249548
2-萘磺酸, technical grade, 70%,
物種
human
186341
1-萘磺酸, >50%,
物種
human
N5602
1-萘基磷酸酯, 99%,
物種
human
C8863
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
物種
human
CDS023580
帕唑帕尼, ,
物種
human

Proteins

產品編號
描述
物種
L2792
LCK，活性，GST 标记 人, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
物種
human