ITCH
itchy E3 ubiquitin protein ligase
同義詞:
AIF4, AIP4, NAPP1, dJ468O1.1
物種:
Human ITCH (83737), Mouse Itch (16396), Rat Itch (311567), chicken ITCH (419145), Zebrafish itch (100331274), cow ITCH (508431), dog ITCH (477199), domestic guinea pig Itch (100724288), Horse ITCH (100069340), domestic cat ITCH (101086133) ...更多
UniProtKB ID:
基因 ID:
- Human(83737) Summary: This gene encodes a member of the Nedd4 family of HECT domain E3 ubiquitin ligases. HECT domain E3 ubiquitin ligases transfer ubiquitin from E2 ubiquitin-conjugating enzymes to protein substrates, thus targeting specific proteins for lysosomal degradation. The encoded protein plays a role in multiple cellular processes including erythroid and lymphoid cell differentiation and the regulation of immune responses. Mutations in this gene are a cause of syndromic multisystem autoimmune disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
- Mouse(16396) itchy, E3 ubiquitin protein ligase
- Rat(311567) itchy E3 ubiquitin protein ligase
- chicken(419145) itchy E3 ubiquitin protein ligase
- Zebrafish(100331274) itchy E3 ubiquitin protein ligase homolog (mouse)
- cow(508431) itchy E3 ubiquitin protein ligase homolog (mouse)
- dog(477199) itchy E3 ubiquitin protein ligase
- domestic guinea pig(100724288) itchy E3 ubiquitin protein ligase
- Horse(100069340) itchy E3 ubiquitin protein ligase
- domestic cat(101086133) itchy E3 ubiquitin protein ligase
- sheep(101118041) itchy E3 ubiquitin protein ligase
- naked mole-rat(101711522) itchy E3 ubiquitin protein ligase
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Antibodies
產品編號
描述
物種活性
應用
Anti-ITCH antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
物種活性
human, monkey
應用
western blot
esiRNA
產品編號
描述
物種