ING3
inhibitor of growth family, member 3
同義詞:
Eaf4, ING2, MEAF4, p47ING3
物種:
Human ING3 (54556), Mouse Ing3 (71777), Rat Ing3 (312154), domestic guinea pig Ing3 (100721269), sheep ING3 (101102722), cow ING3 (513000), dog ING3 (475299), Zebrafish ing3 (393911), naked mole-rat Ing3 (101711218), domestic cat ING3 (101089592) ...更多
UniProtKB ID:
基因 ID:
- Human(54556) Summary: The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed. [provided by RefSeq, Jul 2008]
- Mouse(71777) inhibitor of growth family, member 3
- Rat(312154) inhibitor of growth family, member 3
- domestic guinea pig(100721269) inhibitor of growth family, member 3
- sheep(101102722) inhibitor of growth family, member 3
- cow(513000) inhibitor of growth family, member 3
- dog(475299) inhibitor of growth family, member 3
- Zebrafish(393911) inhibitor of growth family, member 3
- naked mole-rat(101711218) inhibitor of growth family, member 3
- domestic cat(101089592) inhibitor of growth family, member 3
- chicken(417762) inhibitor of growth family, member 3
- Horse(100056220) inhibitor of growth family, member 3
- fruit fly(32853) CG6632 gene product from transcript CG6632-RA
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Antibodies
產品編號
描述
物種活性
應用
Anti-ING3 Antibody, clone 2A2, clone 2A2, from mouse,
物種活性
human, mouse
應用
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-ING3 antibody produced in mouse, clone 2C4, purified immunoglobulin, buffered aqueous solution,
物種活性
human, mouse, rat
應用
ELISA
immunofluorescence
western blot
immunofluorescence
western blot