HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
同義詞:
DP(W3), DP(W4), HLA-DP1A, HLADP, HLASB, PLT1
物種:
UniProtKB ID:
基因 ID:
- Human(3113) Summary: HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules. [provided by RefSeq, Jul 2008]
- Zebrafish(553497) HLA-DPA1 protein
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Antibodies
產品編號
描述
物種活性
應用
Anti-HLA-DP alpha 1 antibody, Rabbit monoclonal, recombinant, expressed in proprietary host, clone SP228, affinity isolated antibody,
物種活性
human
應用
flow cytometry
immunohistochemistry
immunohistochemistry