H2AFZ
H2A histone family, member Z
同義詞:
H2A.Z-1, H2A.z, H2A/z, H2AZ
物種:
Human H2AFZ (3015), Mouse H2afz (51788), Rat H2afz (58940), Zebrafish h2afz (573415), cow H2AFZ (287016), chicken H2AFZ (426361), dog H2AFZ (478493), sheep H2AFZ (443235)
UniProtKB ID:
基因 ID:
- Human(3015) Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality. [provided by RefSeq, Jul 2008]
- Mouse(51788) H2A histone family, member Z
- Rat(58940) H2A histone family, member Z
- Zebrafish(573415) H2A histone family, member Z
- cow(287016) H2A histone family, member Z
- chicken(426361) H2A histone family, member Z
- dog(478493) H2A histone family, member Z
- sheep(443235) histone H2A.Z
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