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Merck

GRIN2A

glutamate receptor, ionotropic, N-methyl D-aspartate 2A

同義詞:
EPND, GluN2A, NMDAR2A, NR2A
物種:
Human GRIN2A (2903), Mouse Grin2a (14811), Rat Grin2a (24409), sheep GRIN2A (101106989), domestic guinea pig Grin2a (100727265), dog GRIN2A (490012), chicken GRIN2A (427678), domestic cat GRIN2A (101086110)
UniProtKB ID:
Q12879, O00669, Q17RZ6
基因 ID:
  • Human(2903) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate-gated ion channels. These receptors have been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) and NMDAR2D (GRIN2D). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
  • Mouse(14811) glutamate receptor, ionotropic, NMDA2A (epsilon 1)
  • Rat(24409) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • sheep(101106989) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic guinea pig(100727265) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • dog(490012) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • chicken(427678) glutamate receptor, ionotropic, N-methyl D-aspartate 2A
  • domestic cat(101086110) glutamate receptor, ionotropic, N-methyl D-aspartate 2A

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Small Molecule - Agonist

產品編號
描述
物種
239488
1,4-双(3-氨丙基)哌嗪, ≥99%,
物種
rat
D-013
右美沙芬 溶液, 1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
1181007
右美沙芬 氢溴酸盐, United States Pharmacopeia (USP) Reference Standard,
物種
human
PHR1018
右美沙芬 氢溴酸盐 一水合物, certified reference material, pharmaceutical secondary standard,
物種
human
D9684
右美沙芬 氢溴酸盐, meets USP testing specifications,
物種
human

Small Molecule - Allosteric Modulator

產品編號
描述
物種
561479
4-氨基哌啶, ,
物種
rat
K-002
盐酸氯胺酮标准液 盐酸盐 溶液, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
物種
human
K2753
(±)-氯胺酮 盐酸盐, solid,
物種
human
K1884
S-(+)-Ketamine hydrochloride, ,
物種
human
Y0000450
(±)-氯胺酮 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human

Small Molecule - Antagonist

產品編號
描述
物種
G7126
甘氨酸, ReagentPlus®, ≥99% (HPLC),
物種
rat
G8898
甘氨酸, suitable for electrophoresis, ≥99%,
物種
rat
50046
甘氨酸, BioUltra, for molecular biology, ≥99.0% (NT),
物種
rat
G8790
甘氨酸, from non-animal source, meets EP, JP, USP testing specifications, suitable for cell culture, ≥98.5%,
物種
rat
G5417
甘氨酸, ,
物種
rat

Antibodies

產品編號
描述
物種活性
應用
04-901
抗 NR2A 抗体，克隆 A12W，兔单克隆, culture supernatant, clone A12W, Upstate®,
物種活性
mouse, rat
應用
western blot
07-632
抗-NR2A抗体, Upstate®, from rabbit,
物種活性
mouse, rat
應用
immunoprecipitation (IP)
western blot
AB1555P
抗-NMDAR2A抗体, Chemicon®, from rabbit,
物種活性
fish, human, mouse, rat
應用
immunohistochemistry
immunoprecipitation (IP)
western blot
SAB5200888
Monoclonal Anti-Glun2A/Nr2A antibody produced in mouse, clone S327-95, purified immunoglobulin,
物種活性
human, mouse, rat
應用
immunocytochemistry
immunohistochemistry
western blot
AB1555
抗-NMDAR2A抗体, serum, Chemicon®,
物種活性
fish, human, mouse, rat
應用
immunoprecipitation (IP)
western blot

Small Molecule - Blocker

產品編號
描述
物種
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
物種
human
A7127
胍丁胺 硫酸盐, ≥97%, powder,
物種
human
75517
奥芬那君 盐酸盐, ≥98.0% (AT),
物種
human
Y0000100
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human
Y0001181
奥芬那君 盐酸盐, European Pharmacopoeia (EP) Reference Standard,
物種
human

Small Molecule - Inhibitor

產品編號
描述
物種
I5109
吲哚-2-羧酸, 98%,
物種
rat, human
D207756
二苯胍, 97%,
物種
rat, mouse, human
Q2128
使君子氨酸, powder,
物種
rat
N5501
Nω-硝基-L-精氨酸, ≥98% (TLC),
物種
rat, mouse, human
P0547
喷他脒 羟乙基磺酸盐, powder,
物種
human

Small Molecule - Mixed Agonist/Antagonist

產品編號
描述
物種
D23602
1,3-二氨基丙烷, ≥99%,
物種
rat
308110
N,N′-二甲基-1,3-丙二胺, 97%,
物種
rat
549983
N , N , N ′,N'-四甲基-1,3-丙二胺, ≥99%,
物種
rat
D18609
1,3-二氨基-2-丙醇, 95%,
物種
rat
127027
N-甲基-1,3-二氨基丙烷, 98%,
物種
rat

esiRNA

產品編號
描述
物種
EHU040271
MISSION® esiRNA, targeting human GRIN2A,
物種
human